@article{oai:repo.qst.go.jp:00047536,
 author = {Ishikawa, Hitoshi and Katoh, Hiroyuki and Kaminuma, Takuya and Kawamura, Hidemasa and Ito, Kazuto and Matsui, Hiroshi and Hirato, Junko and Shimizu, Nobuaki and Takezawa, Yutaka and Tsuji, Hiroshi and Suzuki, Kazuhiro and Ohno, Tatsuya and Nakano, Takashi and 辻 比呂志},
 issue = {10},
 journal = {Anticancer research},
 month = {Oct},
 note = {AIM: 
 To prospectively evaluate the feasibility of carbon-ion radiotherapy (C-ion RT) for prostate cancer using a new compact-sized accelerator.
 PATIENTS AND METHODS: 
 Seventy-six patients underwent C-ion RT at our center using a recommended dose fractionation of 57.6 GyE in 16 fractions established at the National Institute of Radiological Sciences. Health-related Quality of Life (HRQOL) assessment was also performed using the Medical Outcome Study 8-items Short Form Health Survey (SF-8) questionnaire.
 RESULTS: 
 The median follow-up time was 51 months (range=8-58 months). Grade 2 gastrointestinal and genitourinary complications developed in 1 (1.3%) and 5 (6.6%) patients, respectively. Recurrences occurred in 4 patients, and the 4-year biochemical relapse-free rate was 94.6%. The HRQOL scores after C-ion RT were objectively well-maintained.
 CONCLUSION: 
 Irrespective of the small number of patients of the study, C-ion RT for prostate cancer using the first commercial-based accelerator reproduced the toxicity outcomes at the NIRS.},
 pages = {5559--5566},
 title = {Carbon-ion Radiotherapy for Prostate Cancer: Analysis of Morbidities and Change in Health-related Quality of Life.},
 volume = {35},
 year = {2015}
}