@article{oai:repo.qst.go.jp:00047448,
 author = {Akashita, Shiho and Tachibana, Yasuhiko and Sakamaki, Kentaro and Sogawa, Keiji and Inoue, Tomio and 立花 泰彦 and 井上 登美夫},
 issue = {3},
 journal = {Japanese Journal of Radiology},
 month = {Mar},
 note = {PURPOSE:
To evaluate the feasibility of the iterative reconstruction (IR) method with low-dose multi-detector computed tomography (MDCT) for lung cancer screening.
MATERIALS AND METHODS:
A chest CT phantom containing simulated ground-glass nodules (GGNs) of 5 different sizes was scanned by use of 16-row and 64-row MDCT. Tube currents of 10, 20, and 30 mA were used for the low-dose CT. To assess the detectability of pure GGNs, a radiologist-performance test was conducted. Mean visual scores for simulated GGNs were compared for reconstructed images from filtered back-projection (FBP) and the IR method.
RESULTS:
When 64-row MDCT was used, visual scores for simulated GGNs were significantly higher for the IR method than for the FBP method under any conditions; scores were also significantly higher for 16-row MDCT under some conditions.
CONCLUSIONS:
The results of this experimental chest phantom study showed that use of the IR method improved the detectability of simulated pure GGNs.},
 pages = {113--121},
 title = {Detection of pure ground-glass nodules in the lung by low-dose multi-detector computed tomography, with use of an iterative reconstruction method: a comparison with conventional image reconstruction by the filtered back-projection method.},
 volume = {33},
 year = {2015}
}