@article{oai:repo.qst.go.jp:00047419, author = {Murayama, Shuhei and Jo, Jun-Ichiro and Arai, Kazutaka and Nishikido, Fumihiko and Bakalova, Rumiana and Yamaya, Taiga and Saga, Tsuneo and Kato, Masaru and Aoki, Ichio and 村山 周平 and 錦戸 文彦 and バカロバ ルミアナ and 山谷 泰賀 and 佐賀 恒夫 and 加藤 大 and 青木 伊知男}, issue = {23}, journal = {Analytical chemistry}, month = {Dec}, note = {We previously have developed the photoresponsive tetra-gel and nanoparticles for controlling the function of the encapsulated substance by UV irradiation. However, the penetration ability of the UV is not high enough. Here, we developed a radiation-responsive tetra-gel and nanoparticle based on γ-ray-responsive X-shaped polyethylene glycol (PEG) linker with a disulfide bond. The nanoparticle could retain small molecules and biomacromolecules. γ-Rays were used as a trigger signal because of their higher penetrating ability. This allowed a spatiotemporal release and control of the encapsulated substances from the nanoparticle in the deeper region, which is impossible by using light exposure (ultraviolet, visible, and near-infrared).}, pages = {11625--11629}, title = {γ-PARCEL: Control of Molecular Release Using γ-Rays.}, volume = {87}, year = {2015} }