{"created":"2023-05-15T14:36:43.243134+00:00","id":47306,"links":{},"metadata":{"_buckets":{"deposit":"5b1d46de-7414-4acb-88b8-20e4acf4cbb2"},"_deposit":{"created_by":1,"id":"47306","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"47306"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00047306","sets":["1"]},"author_link":["473181","473175","473172","473171","473177","473176","473174","473178","473179","473182","473180","473173"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2003-05","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"183","bibliographicPageStart":"179","bibliographicVolumeNumber":"52","bibliographic_titles":[{"bibliographic_title":"Experimental Animals"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The developmental competence of in vitro cultured embryos vitrified-warmed at an early cleavage stage (2- or 4, 8-cell stage) was examined by both direct transfer into recipient animals and after in vitro manipulation for chimeric mice production using embryonic stem (ES) cells.  Vitrified-warmed embryos transferred at the morulae and blastocyst stages showed fetus development comparable to control embryos, although blastocyst development of vitrified-warmed embryos was significantly slower than that of controls.  When vitrified-warmed early cleavage stage embryos were used for chimeric mouse production using ES cells, 1 to 10% of the injected or aggregated embryos developed into chimeric neonates and germ-line chimeric mice were obtained from all ES cell lines.  This study indicates that embryos developed in vitro from vitrified-warmed embryos have equivalent competence with unvitrified embryos irrespective of stage of vitrification and that these vitrified-warmed embryos maintain adequate viability even after in vitro manipulation such as aggregation and microinjection with ES cells.","subitem_description_type":"Abstract"}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1341-1357","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kito, Seiji"}],"nameIdentifiers":[{"nameIdentifier":"473171","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Noguchi, Yoshiko"}],"nameIdentifiers":[{"nameIdentifier":"473172","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Oota, Yuki"}],"nameIdentifiers":[{"nameIdentifier":"473173","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ohhata, Tatsuya"}],"nameIdentifiers":[{"nameIdentifier":"473174","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Abe, Masumi"}],"nameIdentifiers":[{"nameIdentifier":"473175","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shiomi, Naoko"}],"nameIdentifiers":[{"nameIdentifier":"473176","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shiomi, Tadahiro"}],"nameIdentifiers":[{"nameIdentifier":"473177","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鬼頭 靖司","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"473178","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"太田 有紀","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"473179","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"安倍 真澄","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"473180","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"塩見 尚子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"473181","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"塩見 忠博","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"473182","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Evaluation of developmental competence of vitrified-warmed early cleavage-stage embryos and their application for chimeric mouse production","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Evaluation of developmental competence of vitrified-warmed early cleavage-stage embryos and their application for chimeric mouse production"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-09-16"},"publish_date":"2015-09-16","publish_status":"0","recid":"47306","relation_version_is_last":true,"title":["Evaluation of developmental competence of vitrified-warmed early cleavage-stage embryos and their application for chimeric mouse production"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:41:21.515337+00:00"}