@article{oai:repo.qst.go.jp:00047169,
 author = {Nomiya, Takuma and Akamatsu, Hiroko and Harada, Mayumi and Ota, Ibuki and Hagiwara, Yasuhito and Ichikawa, Mayumi and Miwa, Misako and Kawashiro, Shouhei and Hagiwara, Motohisa and Chin, Masahiro and Hashizume, Eiji and Nemoto, Kenji and 野宮 琢磨},
 issue = {48},
 journal = {World journal of gastroenterology : WJG},
 month = {Dec},
 note = {A clinical trial of radiotherapy with modified simultaneous integrated boost (SIB) technique against huge tumors was conducted. A 58-year-old male patient who had a huge pelvic tumor diagnosed as a rectal adenocarcinoma due to familial adenomatous polyposis was enrolled in this trial. The total dose of 77 Gy (equivalent dose in 2 Gy/fraction) and 64.5 Gy was delivered to the center of the tumor and the surrounding area respectively, and approximately 20% dose escalation was achieved with the modified SIB technique. The tumor with an initial maximum size of 15 cm disappeared 120 d after the start of the radiotherapy. Performance status of the patient improved from 4 to 0. Radiotherapy with modified SIB may be effective for patients with a huge tumor in terms of tumor shrinkage/disappearance, improvement of QOL, and prolongation of survival.},
 pages = {18480--18486},
 title = {Modified simultaneous integrated boost radiotherapy for an unresectable huge refractory pelvic tumor diagnosed as a rectal adenocarcinoma.},
 volume = {20},
 year = {2014}
}