@article{oai:repo.qst.go.jp:00047111, author = {Gündüz, Serhat and Nitta, Nobuhiro and Vibhute, Sandip and Shibata, Sayaka and Martin, E. Mayer and Nikos K. Logothetis and Aoki, Ichio and Angelovski, Goran and 新田 展大 and 柴田 さやか and 青木 伊知男}, journal = {Chemical Communications}, month = {Dec}, note = {We report a methodology which enables the preparation of dendrimeric contrast agents sensitive to Ca2+ when starting from the monomeric analogue. The Ca-triggered longitudinal relaxivity response of these agents is not compromised by undertaking synthetic transformations, despite structural changes. The in vivo MRI studies in the rat cerebral cortex indicate that diffusion properties of dendrimeric contrast agents have great advantages as compared to their monomeric equivalents.}, pages = {2782--2785}, title = {Dendrimeric calcium-responsive MRI contrast agents with slow in vivo diffusion}, volume = {14}, year = {2014} }