@article{oai:repo.qst.go.jp:00046861, author = {Suhara, Tetsuya and Y, Sudo and K, Yoshida and Okubo, Yoshiro and H, Fukuda and Obata, Takayuki and Yoshikawa, Kyosan and Suzuki, Kazuo and Y, Sasaki and 須原 哲也 and 大久保 善朗 and 小畠 隆行 and 吉川 京燦 and 鈴木 和夫}, issue = {9099}, journal = {Lancet}, month = {Jan}, note = {Although high-affinity imipramine binding sites have been reported in both rat and human lung, the role of the lungs in the pharmacokinetics of antidepressants has not received much attention. Substantial accumulation of selective serotonin-reuptake inhibitors (SSRIs) in the lungs has been reported. We have investigated the role of the lungs in pharmacokinetic drug interactions between tricyclic antidepressants and SSRIs.}, pages = {332--335}, title = {Lung as reservoir for antidepressants in pharmacokinetic drug interactions}, volume = {351}, year = {1998} }