{"created":"2023-05-15T14:36:17.209425+00:00","id":46714,"links":{},"metadata":{"_buckets":{"deposit":"c27ed15c-6625-4dd7-bcb4-47c4b61feeb1"},"_deposit":{"created_by":1,"id":"46714","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"46714"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00046714","sets":["1"]},"author_link":["465780","465791","465788","465779","465781","465783","465786","465787","465789","465792","465784","465785","465790","465782","465778"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"410","bibliographicPageStart":"401","bibliographicVolumeNumber":"89","bibliographic_titles":[{"bibliographic_title":"International Journal of Radiation Biology"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Purpose : The impact of the damage distribution to cellular\nsurvival and chromosomal aberrations following high Linear\nEnergy Transfer (LET) radiation was investigated.\nMaterials and methods : High LET iron-ions (500 MeV/n, LET\n200 keV/ um) were delivered to G1-phase synchronized Chinese\nHamster Ovary (CHO) cells located at a vertical or horizontal\nangle relative to the ion beam in order to give same dose but\ndiff erent fl uence and damage distribution.\nResults : Horizontal irradiation produced DNA double-strand\nbreak (DSB) along each ion track represented as clustered lines,\nand vertical irradiation produced a greater fl uence. The initial\ndamages measured by premature chromosome condensation\nwere equal per dose in both irradiation types. Horizontal\nirradiation proved to be less eff ective in cell killing than vertical\nat doses of more than 3 Gy. Vertical irradiation produced a higher\nnumber of metaphase chromosomal aberrations compared\nto horizontally irradiated samples. In particular, formation of\nexchange-type aberrations was the same, but that of deletiontype\naberrations were signifi cantly higher after vertical\nirradiation than horizontal irradiation.\nConclusions : Therefore, we concluded that high fl uence per dose\nis more eff ective than low fl uence per dose to produce radiationinduced\nchromosomal aberrations and to kill exposed cells\nfollowing high LET heavy-ion exposure.","subitem_description_type":"Abstract"}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0955-3002","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Fujii, Yoshihiro"}],"nameIdentifiers":[{"nameIdentifier":"465778","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Chuck, Yurkon"}],"nameIdentifiers":[{"nameIdentifier":"465779","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Maeda, Jyunko"}],"nameIdentifiers":[{"nameIdentifier":"465780","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Genet, Stefan"}],"nameIdentifiers":[{"nameIdentifier":"465781","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Okayasu, Ryuichi"}],"nameIdentifiers":[{"nameIdentifier":"465782","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kitamura, Hisashi"}],"nameIdentifiers":[{"nameIdentifier":"465783","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fujimori, Akira"}],"nameIdentifiers":[{"nameIdentifier":"465784","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kato, Takamitsu"}],"nameIdentifiers":[{"nameIdentifier":"465785","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"藤井 義大","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"465786","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ｃｈｕｃｋ Ｙｕｒｋｏｎ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"465787","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ｍａｅｄａ Ｊｙｕｎｋｏ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"465788","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"岡安 隆一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"465789","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"北村 尚","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"465790","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"藤森 亮","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"465791","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"加藤 宝光","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"465792","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Influence of track directions on the biological consequences in cells irradiated with high LET heavy ions","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Influence of track directions on the biological consequences in cells irradiated with high LET heavy ions"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-02-06"},"publish_date":"2014-02-06","publish_status":"0","recid":"46714","relation_version_is_last":true,"title":["Influence of track directions on the biological consequences in cells irradiated with high LET heavy ions"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:48:30.214395+00:00"}