{"created":"2023-05-15T14:36:14.338400+00:00","id":46649,"links":{},"metadata":{"_buckets":{"deposit":"966b242e-02c9-4812-8d6c-36cabe846825"},"_deposit":{"created_by":1,"id":"46649","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"46649"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00046649","sets":["1"]},"author_link":["465045","465047","465040","465048","465044","465043","465039","465050","465041","465046","465049","465042"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-02","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"42","bibliographicPageStart":"536","bibliographicVolumeNumber":"6","bibliographic_titles":[{"bibliographic_title":"International Journal of Clinical and Experimental Pathology (Online Only URL:http://www.ijcep.com/)"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We report a first case of HIV-associated lymphoma (HAL) presenting with acute kidney injury (AKI) and inflammatory immune reconstitution syndrome (IRIS). A 39-year-old male, treated with nonsteroidal anti-inflammatory drugs (NSAIDs) for one month prior to admission, developed AKI, left testicular tumor, and recurrent swelling of the right parotid gland. A resected testicular tumor exhibited features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma. Renal biopsy showed hydro-degeneration of renal tubules, interstitial inflammatory cells, and a small number of lymphoma cells in the sub-capsule, compatible with acute interstitial nephritis. His renal dysfunction rapidly recovered following chemotherapy and combination antiretroviral therapy (cART). He developed pneumonia concomitantly with a decrease in HIV-RNA level and an increase in CD4+ cells after the first cycle of chemotherapy, which spontaneously resolved after the second cycle of chemotherapy without additional anti-infection drugs; thus, his pneumonia fulfilled the diagnostic criteria for IRIS. We suggest that IRIS may frequently develop during chemotherapy for HAL, but may be overlooked. He was coinfected with hepatitis B virus (HBV), which genotypes known as is associated with liver-related mortality and response to antiviral therapy; recently, an intimate interplay between HIV and HBV in the onset of lymphoma has been reported. Therefore, we addressed the HBV genotype in the patient. The analysis revealed that he exhibited a mixed genotype (A/E) not native to Japan and primarily found in Europe and North America or West Africa. These findings suggest that universal vaccination for juveniles against HBV is warranted in Japan.","subitem_description_type":"Abstract"}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1936-2625","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Tajima, Katsushi"}],"nameIdentifiers":[{"nameIdentifier":"465039","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kohno, Kei"}],"nameIdentifiers":[{"nameIdentifier":"465040","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shiono, Yosuke"}],"nameIdentifiers":[{"nameIdentifier":"465041","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suzuki, Ikuko"}],"nameIdentifiers":[{"nameIdentifier":"465042","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kato, Yuichi"}],"nameIdentifiers":[{"nameIdentifier":"465043","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hiroshima, Yuki"}],"nameIdentifiers":[{"nameIdentifier":"465044","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamamoto, Masakazu"}],"nameIdentifiers":[{"nameIdentifier":"465045","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ohtake, Hiroya"}],"nameIdentifiers":[{"nameIdentifier":"465046","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Iwaba, Akiko"}],"nameIdentifiers":[{"nameIdentifier":"465047","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamakawa, Mitsunori"}],"nameIdentifiers":[{"nameIdentifier":"465048","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kato, Takeo"}],"nameIdentifiers":[{"nameIdentifier":"465049","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田嶋 克史","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"465050","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Acute kidney injury and inflammatory immune reconstitution syndrome in mixed genotype (A/E) hepatitis B virus co-infection in HIV-associated lymphoma","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Acute kidney injury and inflammatory immune reconstitution syndrome in mixed genotype (A/E) hepatitis B virus co-infection in HIV-associated lymphoma"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-12-02"},"publish_date":"2013-12-02","publish_status":"0","recid":"46649","relation_version_is_last":true,"title":["Acute kidney injury and inflammatory immune reconstitution syndrome in mixed genotype (A/E) hepatitis B virus co-infection in HIV-associated lymphoma"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:49:15.698171+00:00"}