{"created":"2023-05-15T14:36:14.208185+00:00","id":46646,"links":{},"metadata":{"_buckets":{"deposit":"f029a718-23ec-4134-b894-c0e6b646bbdb"},"_deposit":{"created_by":1,"id":"46646","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"46646"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00046646","sets":["1"]},"author_link":["465011","465012","465018","465016","465020","465022","465010","465007","465015","465013","465021","465014","465009","465019","465008","465006","465017"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-09","bibliographicIssueDateType":"Issued"},"bibliographic_titles":[{"bibliographic_title":"Breast cancer (Tokyo, Japan)"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"PURPOSE: To evaluate the efficacy and safety of hypofractionated whole-breast irradiation (HF-WBI) compared with conventionally fractionated (CF) WBI. MATERIALS AND METHODS: Patients with early breast cancer (stages 0-II and <3 positive lymph nodes) who had undergone breast-conserving surgery were eligible for the HF-WBI study. HF-WBI was administered at 43.2 Gy in 16 fractions over 3.2 weeks to the whole breast with an additional tumor-bed boost of 8.1 Gy in 3 fractions over 3 days for positive surgical margins or those <5 mm. CF-WBI was administered at 50 Gy in 25 fractions over 5 weeks to the whole breast with an additional tumor-bed boost of 16 Gy in 8 fractions over 1.4 weeks to 6 Gy in 3 fractions over 3 days, depending on margin status. RESULTS: From April 1, 2006, to December 31, 2010, 717 patients were registered and 734 breasts were treated by HF-WBI. In the same period, 381 patients and 393 breasts who matched the study criteria chose CF-WBI, so the total number of patients in this comparison was 1,098. Grade 2 acute skin reactions were observed for 24 patients (3 %) in the HF-WBI group and 53 patients (14 %) in the CF-WBI (p < 0.001) group. The median follow-up period was 27 months. Two cases of intrabreast tumor recurrence were observed in each treatment group. Regional lymph node recurrence was observed in 1 HF-WBI patient and 2 CF-WBI patients. CONCLUSION: HF-WBI is superior to CF-WBI in terms of acute skin reaction and has the same short-term efficacy.","subitem_description_type":"Abstract"}]},"item_8_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Springer"}]},"item_8_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"22968629","subitem_relation_type_select":"PMID"}}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1007/s12282-012-0406-6","subitem_relation_type_select":"DOI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1340-6868","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Karasawa, Kumiko"}],"nameIdentifiers":[{"nameIdentifier":"465006","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kunogi, Hiroaki"}],"nameIdentifiers":[{"nameIdentifier":"465007","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hirai, Takahisa"}],"nameIdentifiers":[{"nameIdentifier":"465008","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hojo, Hidehiro"}],"nameIdentifiers":[{"nameIdentifier":"465009","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hirowatari, Hisako"}],"nameIdentifiers":[{"nameIdentifier":"465010","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Izawa, Hiromi"}],"nameIdentifiers":[{"nameIdentifier":"465011","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ito, Kana"}],"nameIdentifiers":[{"nameIdentifier":"465012","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sasai, Keisuke"}],"nameIdentifiers":[{"nameIdentifier":"465013","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kawashima, Motohiro"}],"nameIdentifiers":[{"nameIdentifier":"465014","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Furuya, Tomohisa"}],"nameIdentifiers":[{"nameIdentifier":"465015","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sugimoto, Satoru"}],"nameIdentifiers":[{"nameIdentifier":"465016","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kurokawa, Chie"}],"nameIdentifiers":[{"nameIdentifier":"465017","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ozawa, Shuichi"}],"nameIdentifiers":[{"nameIdentifier":"465018","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Saito, Mitsue"}],"nameIdentifiers":[{"nameIdentifier":"465019","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"唐澤 久美子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"465020","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"平井 崇久","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"465021","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"川嶋 基敬","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"465022","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Comparison of hypofractionated and conventionally fractionated whole-breast irradiation for early breast cancer patients: a single-institute study of 1,098 patients.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Comparison of hypofractionated and conventionally fractionated whole-breast irradiation for early breast cancer patients: a single-institute study of 1,098 patients."}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-11-27"},"publish_date":"2013-11-27","publish_status":"0","recid":"46646","relation_version_is_last":true,"title":["Comparison of hypofractionated and conventionally fractionated whole-breast irradiation for early breast cancer patients: a single-institute study of 1,098 patients."],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:49:17.875680+00:00"}