{"created":"2023-05-15T14:36:13.292510+00:00","id":46625,"links":{},"metadata":{"_buckets":{"deposit":"bbf6e9a8-24b5-497e-b1a8-325fe99cf25b"},"_deposit":{"created_by":1,"id":"46625","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"46625"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00046625","sets":["1"]},"author_link":["464831","464834","464826","464832","464828","464837","464827","464833","464830","464841","464842","464838","464829","464836","464840","464835","464839"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-08","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"7","bibliographicPageEnd":"778","bibliographicPageStart":"770","bibliographicVolumeNumber":"22","bibliographic_titles":[{"bibliographic_title":"NMR in Biomedicine"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"A new interpretation is proposed for stimulus-induced signal changes in diffusion-weighted functional MRI. T(2)-weighted spin-echo echo-planar images were acquired at different diffusion-weightings while visual stimulation was presented to human volunteers. The amplitudes of the positive stimulus-correlated response and post-stimulus undershoot (PSU) in the functional time-courses were found to follow different trends as a function of b-value. Data were analysed using a three-compartment signal model, with one compartment being purely vascular and the other two dominated by fast- and slow-diffusing molecules in the brain tissue. The diffusion coefficients of the tissue were assumed to be constant throughout the experiments. It is shown that the stimulus-induced signal changes can be decomposed into independent contributions originating from each of the three compartments. After decomposition, the fast-diffusion phase displays a substantial PSU, while the slow-diffusion phase demonstrates a highly reproducible and stimulus-correlated time-course with minimal undershoot. The decomposed responses are interpreted in terms of the spin-echo blood oxygenation level dependent (SE-BOLD) effect, and it is proposed that the signal produced by fast- and slow-diffusing molecules reflect a sensitivity to susceptibility changes in arteriole/venule- and capillary-sized vessels, respectively. This interpretation suggests that diffusion-weighted SE-BOLD imaging may provide subtle information about the haemodynamic and neuronal responses. Copyright (c) 2009 John Wiley & Sons, Ltd.","subitem_description_type":"Abstract"}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0952-3480","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kershaw, Jeffrey"}],"nameIdentifiers":[{"nameIdentifier":"464826","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tomiyasu, Moyoko"}],"nameIdentifiers":[{"nameIdentifier":"464827","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kashikura, Kenichi"}],"nameIdentifiers":[{"nameIdentifier":"464828","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hirano, Yoshiyuki"}],"nameIdentifiers":[{"nameIdentifier":"464829","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nonaka, Hiroi"}],"nameIdentifiers":[{"nameIdentifier":"464830","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ikehira, Hiroo"}],"nameIdentifiers":[{"nameIdentifier":"464831","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kanno, Iwao"}],"nameIdentifiers":[{"nameIdentifier":"464832","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Obata, Takayuki"}],"nameIdentifiers":[{"nameIdentifier":"464833","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"et.al"}],"nameIdentifiers":[{"nameIdentifier":"464834","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ｋｅｒｓｈａｗ Ｊｅｆｆｒｅｙ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"464835","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"富安 もよこ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"464836","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"柏倉 健一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"464837","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"平野 好幸","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"464838","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"野中 博意","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"464839","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"池平 博夫","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"464840","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"菅野 巖","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"464841","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小畠 隆行","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"464842","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"A multi-compartmental SE-BOLD interpretation for stimulus-related signal changes in diffusion-weighted functional MRI","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"A multi-compartmental SE-BOLD interpretation for stimulus-related signal changes in diffusion-weighted functional MRI"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-11-25"},"publish_date":"2013-11-25","publish_status":"0","recid":"46625","relation_version_is_last":true,"title":["A multi-compartmental SE-BOLD interpretation for stimulus-related signal changes in diffusion-weighted functional MRI"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:49:32.889871+00:00"}