{"created":"2023-05-15T14:36:12.400543+00:00","id":46605,"links":{},"metadata":{"_buckets":{"deposit":"858b3578-26ec-467b-8ccb-8f70cb9d2c17"},"_deposit":{"created_by":1,"id":"46605","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"46605"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00046605","sets":["1"]},"author_link":["464593","464586","464595","464599","464602","464596","464603","464604","464598","464587","464592","464600","464591","464590","464597","464589","464594","464601","464588"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"51","bibliographicPageStart":"45","bibliographicVolumeNumber":"119","bibliographic_titles":[{"bibliographic_title":"Cancer"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"BACKGROUND: The authors evaluated the tolerance and efficacy of carbon-ion radiotherapy (CIRT) as a short-course, preoperative treatment and determined the recommended dose needed to reduce the risk of postoperative local recurrence without excess injury to normal tissue.\nMETHODS: Patients radiographically defined with potentially resectable pancreatic cancer were eligible. A preoperative, short-course, dose-escalation study was performed with fixed 8 fractions in 2 weeks. The dose of irradiation was increased by 5% increments from 30 grays equivalents (GyE) to 36.8 GyE. Surgery was to be performed 2 to 4 weeks after the completion of CIRT.\nRESULTS: The study enrolled 26 patients. At the time of restaging after CIRT, disease progression with distant metastasis or refusal ruled out 5 patients from surgery. Twenty-one of 26 patients (81%) patients underwent surgery. The pattern of initial disease progression was distant metastasis in 17 patients (65%) and regional recurrence in 2 patients (8%). No patients experienced local recurrence. The 5-year survival rates for all 26 patients and for those who underwent surgery were 42% and 52%, respectively.\nCONCLUSIONS: Preoperative, short-course CIRT followed by surgery is feasible and tolerable without unacceptable morbidity. Cancer 2013. © 2012 American Cancer Society.","subitem_description_type":"Abstract"}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1002/cncr.27723","subitem_relation_type_select":"DOI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0008-543X","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Shinoto, Makoto"}],"nameIdentifiers":[{"nameIdentifier":"464586","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamada, Shigeru"}],"nameIdentifiers":[{"nameIdentifier":"464587","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yasuda, Shigeo"}],"nameIdentifiers":[{"nameIdentifier":"464588","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Imada, Hiroshi"}],"nameIdentifiers":[{"nameIdentifier":"464589","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shioyama, Yoshiyuki"}],"nameIdentifiers":[{"nameIdentifier":"464590","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hiroshi, Honda"}],"nameIdentifiers":[{"nameIdentifier":"464591","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kamada, Tadashi"}],"nameIdentifiers":[{"nameIdentifier":"464592","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsujii, Hirohiko"}],"nameIdentifiers":[{"nameIdentifier":"464593","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Saisho, Hiromitsu"}],"nameIdentifiers":[{"nameIdentifier":"464594","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"et.al"}],"nameIdentifiers":[{"nameIdentifier":"464595","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"篠藤 誠","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"464596","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"山田 滋","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"464597","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"安田 茂雄","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"464598","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今田 浩史","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"464599","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"塩山 善之","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"464600","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"本田  浩","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"464601","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鎌田 正","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"464602","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"辻井 博彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"464603","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"税所 宏光","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"464604","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Phase 1 trial of preoperative, short-course carbon-ion radiotherapy for patients with resectable pancreatic cancer","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Phase 1 trial of preoperative, short-course carbon-ion radiotherapy for patients with resectable pancreatic cancer"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-10-17"},"publish_date":"2013-10-17","publish_status":"0","recid":"46605","relation_version_is_last":true,"title":["Phase 1 trial of preoperative, short-course carbon-ion radiotherapy for patients with resectable pancreatic cancer"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:49:46.918526+00:00"}