@article{oai:repo.qst.go.jp:00046566,
 author = {Okada, Maki and Nakao, Ryuji and Momosaki, Sotaro and Yanamoto, Kazuhiko and Kikuchi, Tatsuya and Okamura, Toshimitsu and Wakizaka, Hidekatsu and Hosoi, Rie and Zhang, Ming-Rong and Inoue, Osamu and 岡田 真希 and 柳本 和彦 and 菊池 達矢 and 岡村 敏充 and 脇坂 秀克 and 細井 理恵 and 張 明栄 and 井上 修},
 journal = {Applied Radiation and Isotopes},
 month = {Apr},
 note = {Abstract: Brain uptake of acetate is insufficient for obtaining a quantitative image of astrocytic oxidative metabolism. To improve brain uptake of [1-11C]acetate, we synthesized benzyl [1-11C]acetate ([1-11C]BA) and conducted a positron emission tomography (PET) study assessing astrocytic oxidative metabolism. Brain uptake of [1-11C]BA was markedly higher compared with [1-11C]acetate, and disappeared with a half-life of 20 minutes in all regions studied. Brain uptake of [1-11C]BA was significantly decreased by fluorocitrate. The results indicate that [1-11C]BA could be a useful PET probe for assessing astrocytic oxidative metabolism.},
 pages = {102--107},
 title = {Improvement of brain uptake for in vivo PET imaging of astrocytic oxidative metabolism using benzyl [1-11C]acetate},
 volume = {78},
 year = {2013}
}