{"created":"2023-05-15T14:35:59.293939+00:00","id":46315,"links":{},"metadata":{"_buckets":{"deposit":"b97687ef-0db9-48f5-96e4-6364ca341c7a"},"_deposit":{"created_by":1,"id":"46315","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"46315"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00046315","sets":["1"]},"author_link":["461391","461397","461392","461395","461400","461398","461402","461393","461401","461399","461396","461394"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-07","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-2","bibliographicPageEnd":"54","bibliographicPageStart":"49","bibliographicVolumeNumber":"712","bibliographic_titles":[{"bibliographic_title":"Fundamental and Molecular Mechanisms of Mutagenesis : A Section of Mutation Research"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Adaptive response (AR) and bystander effect are two important phenomena\ninvolved in biological responses to low doses of ionizing radiation (IR).\nFurthermore, there is a strong interest in better understanding the\nbiological effects of high-LET radiation. We previously demonstrated the\nability of low doses of X-rays to induce an AR to challenging heavy-ion\nradiation (Vares et al., Mutat. Res., 2011). In this study, we assessed in\nvitro the ability of priming low doses (0.01 Gy) of heavy-ion radiation to\ninduce a similar AR to a subsequent challenging dose (1-4 Gy) of high-LET IR\n(carbon-ion: 20 and 40 keV/µm, neon-ion: 150 keV/µm) in TK6, AHH-1 and NH32\ncells. Our results showed that low doses of high-LET radiation can induce an\nAR characterized by lower mutation frequencies at Hypoxanthine-guanine\nphosphoribosyl transferase locus and faster DNA repair kinetics, in cells\nexpressing p53.","subitem_description_type":"Abstract"}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0027-5107","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Vares, Guillaume"}],"nameIdentifiers":[{"nameIdentifier":"461391","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Bing, Wang"}],"nameIdentifiers":[{"nameIdentifier":"461392","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tanaka, Kaoru"}],"nameIdentifiers":[{"nameIdentifier":"461393","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"KAKIMOTO, AYANA"}],"nameIdentifiers":[{"nameIdentifier":"461394","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Eguchi-Kasai, Kiyomi"}],"nameIdentifiers":[{"nameIdentifier":"461395","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nenoi, Mitsuru"}],"nameIdentifiers":[{"nameIdentifier":"461396","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ｇｕｉｌｌａｕｍｅ Ｖａｒｅｓ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"461397","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"王 冰","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"461398","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田中 薫","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"461399","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"柿本 彩七","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"461400","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"笠井 清美","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"461401","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"根井 充","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"461402","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Mutagenic adaptive response to high-LET radiation in human lymphoblastoid cells exposed to low doses of heavy-ion radiation.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Mutagenic adaptive response to high-LET radiation in human lymphoblastoid cells exposed to low doses of heavy-ion radiation."}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-05-07"},"publish_date":"2012-05-07","publish_status":"0","recid":"46315","relation_version_is_last":true,"title":["Mutagenic adaptive response to high-LET radiation in human lymphoblastoid cells exposed to low doses of heavy-ion radiation."],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:53:18.865282+00:00"}