@article{oai:repo.qst.go.jp:00046315,
 author = {Vares, Guillaume and Bing, Wang and Tanaka, Kaoru and KAKIMOTO, AYANA and Eguchi-Kasai, Kiyomi and Nenoi, Mitsuru and Ｇｕｉｌｌａｕｍｅ Ｖａｒｅｓ and 王 冰 and 田中 薫 and 柿本 彩七 and 笠井 清美 and 根井 充},
 issue = {1-2},
 journal = {Fundamental and Molecular Mechanisms of Mutagenesis : A Section of Mutation Research},
 month = {Jul},
 note = {Adaptive response (AR) and bystander effect are two important phenomena
involved in biological responses to low doses of ionizing radiation (IR).
Furthermore, there is a strong interest in better understanding the
biological effects of high-LET radiation. We previously demonstrated the
ability of low doses of X-rays to induce an AR to challenging heavy-ion
radiation (Vares et al., Mutat. Res., 2011). In this study, we assessed in
vitro the ability of priming low doses (0.01 Gy) of heavy-ion radiation to
induce a similar AR to a subsequent challenging dose (1-4 Gy) of high-LET IR
(carbon-ion: 20 and 40 keV/µm, neon-ion: 150 keV/µm) in TK6, AHH-1 and NH32
cells. Our results showed that low doses of high-LET radiation can induce an
AR characterized by lower mutation frequencies at Hypoxanthine-guanine
phosphoribosyl transferase locus and faster DNA repair kinetics, in cells
expressing p53.},
 pages = {49--54},
 title = {Mutagenic adaptive response to high-LET radiation in human lymphoblastoid cells exposed to low doses of heavy-ion radiation.},
 volume = {712},
 year = {2011}
}