@article{oai:repo.qst.go.jp:00046252, author = {Doi, Kazutaka and Mieno, Makiko and Shimada, Yoshiya and Yonehara, Hidenori and Yoshinaga, Shinji and 土居 主尚 and 三重野 牧子 and 島田 義也 and 米原 英典 and 吉永 信治}, issue = {1/3}, journal = {Radiation Protection Dosimetry}, month = {Jul}, note = {Cancer risks among childhood cancer survivors following radiotherapy have not yet been well characterised in terms of radiation dose. A meta-analysis of studies on the excess relative risk per gray (ERR) of second cancer was conducted previously; unfortunately, the small number of eligible studies restricted quantitative valuations. To solve this problem, a statistical method to calculate ERR estimates from other estimates was developed, and a meta-analysis was conducted again. The PubMed database was searched and 26 relevant studies were identified. ERR estimates were available in 15 studies, and for the other 11 studies, the regression-based model was used to calculate ERR estimates from other estimates. The overall ERR estimate was 0.40, which was much lower than that of atomic bomb survivors exposed as young children. Heterogeneity of the risk among studies was suggested, and a further study is needed to explore the heterogeneity among studies.}, pages = {263--267}, title = {META-ANALYSIS OF SECOND CANCER RISK AFTER RADIOTHERAPY AMONG CHILDHOOD CANCER SURVIVORS}, volume = {146}, year = {2011} }