@article{oai:repo.qst.go.jp:00046228,
 author = {Yamaya, Taiga and Yoshida, Eiji and Inaniwa, Taku and Satou, Shinji and Nakajima, Yasunori and Wakizaka, Hidekatsu and Kokuryo, Daisuke and Tsuji, Atsushi and Mitsuhashi, Takayuki and Kawai, Hideyuki and Tashima, Hideaki and Nishikido, Fumihiko and Inadama, Naoko and Murayama, Hideo and Haneishi, Hideaki and Suga, Mikio and Kinouchi, Shoko and 山谷 泰賀 and 吉田 英治 and 稲庭 拓 and 佐藤 眞二 and 中島 靖紀 and 脇坂 秀克 and 國領 大介 and 辻 厚至 and 三橋 隆之 and 河合 秀幸 and 田島 英朗 and 錦戸 文彦 and 稲玉 直子 and 村山 秀雄 and 羽石 秀昭 and 菅 幹生 and 木内 尚子},
 issue = {4},
 journal = {Physics in Medicine and Biology},
 month = {Jan},
 note = {The OpenPET geometry is our new idea to visualize a physically opened space between two detector rings. In this paper, we developed the first small prototype to show a proof-of-concept of OpenPET imaging. Two detector rings of 110 mm diameter and 42 mm axial length were placed with a gap of 42 mm. The basic imaging performance was confirmed through phantom studies; the open imaging was realized at the cost of slight loss of axial resolution and 24% loss of sensitivity. For a proof-of-concept of PET image-guided radiation therapy, we carried out the in-beam tests with 11C radioactive beam irradiation in the heavy ion medical accelerator in Chiba to visualize in situ distribution of primary particles stopped in a phantom. We showed that PET images corresponding to dose distribution were obtained. For an initial proof-of-concept of real-time multimodal imaging, we measured a tumor-inoculated mouse with 18F-FDG, and an optical image of the mouse body surface was taken during the PET measurement by inserting a digital camera in the ring gap. We confirmed that the tumor in the gap was clearly visualized. The result also showed the extension effect of an axial field-of-view (FOV); a large axial FOV of 126 mm was obtained with the detectors that originally covered only an 84 mm axial FOV. In conclusion, our initial imaging studies showed promising performance of the OpenPET.},
 pages = {1123--1137},
 title = {Development of a small prototype for a proof-of-concept of OpenPET imaging},
 volume = {56},
 year = {2011}
}