@article{oai:repo.qst.go.jp:00046223,
 author = {Miyoshi, Norikatsu and Ishii, Hideshi and Nagano, Hiroaki and Haraguchi, Naotsugu and Mimori, Koshi and Saito, Toshiyuki and Ikeda, Masataka and Yamamoto, Hirofumi and Sekimoto, Mitsugu and Doki, Yuichiro and Mori, Masaki and et.al and 石井 秀始 and 齋藤 俊行 and 関本 貢嗣},
 issue = {6},
 journal = {Cell Stem Cell},
 month = {Jun},
 note = {Induced pluripotent stem cells (iPSCs) can be generated from differentiated human and mouse somatic cells using transcription factors such as Oct4, Sox2, Klf4, and c-Myc. It is possible to augment the reprogramming process with chemical compounds, but issues related to low reprogramming efficiencies and, with a number of protocols, residual vector sequences, remain to be resolved. We show here that it is possible to reprogram mouse and human cells to pluripotency by direct transfection of mature double-stranded microRNAs (miRNAs). Our approaches use a combination of mir-200c plus mir-302 s and mir-369 s family miRNAs. Because this reprogramming method does not require vector-based gene transfer, it holds significant potential for biomedical research and regenerative medicine.},
 pages = {633--638},
 title = {Reprogramming of mouse and human cells to pluripotency using mature microRNAs.},
 volume = {8},
 year = {2011}
}