@article{oai:repo.qst.go.jp:00046219,
 author = {Tomiyasu, Moyoko and Inubushi, Toshiro and Nakai, Toshiharu and et.al and 富安 もよこ and 犬伏 俊郎},
 issue = {7},
 journal = {Proceedings of the Japan Academy. Ser. B},
 month = {Jul},
 note = {In order to improve the fat suppression performance of in vivo 13C-MRS operating at 3.0 Tesla, a phantom model study was conducted using a combination of two fat suppression techniques; a set of pulses for frequency (chemical shift) selective suppression (CHESS), and spatial saturation (SAT). By optimizing the slab thickness for SAT and the irradiation bandwidth for CHESS, the signals of the -13CH3 peak at 49 ppm and the -13CH2- peak at 26ppm simulating fat components were suppressed to 5% and 19%, respectively. Combination of these two fat suppression pulses achieved a 53% increase of the height ratio of the glucose C1O peak compared with the sum of all other peaks, indicating better sensitivity for glucose signal detection. This method will be applicable for in vivo 13C-MRS by additional adjustment with the in vivo relaxation times of the metabolites.},
 pages = {425--430},
 title = {Combination of two fat saturation pulses improves detectability of glucose signals in carbon-13 MR spectroscopy},
 volume = {87},
 year = {2011}
}