{"created":"2023-05-15T14:35:49.407336+00:00","id":46087,"links":{},"metadata":{"_buckets":{"deposit":"23cc2907-abf1-4c3b-8ad9-469c97f67a6f"},"_deposit":{"created_by":1,"id":"46087","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"46087"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00046087","sets":["1"]},"author_link":["458791","458795","458789","458793","458796","458790","458792","458794"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-02","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"286","bibliographicPageStart":"278","bibliographicVolumeNumber":"52","bibliographic_titles":[{"bibliographic_title":"Journal of Radiation Research"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Effects of prenatal low-dose irradiations of heavy ions on the postnatal development of mice and of melanocytes have not been well studied. Pregnant females of C57BL/10J mice were irradiated whole-body at 9 days of gestation with a single acute dose of gamma-rays, silicon (Si), argon (Ar) and iron (Fe) ions. The effects were studied by scoring changes in the postnatal development of mice as well as in the pigmentation of cutaneous coats and tail-tips of their offspring 22 days after birth. The survival to day 22 decreased from the offspring exposed to 0.4 Gy of argon and iron ions and to 0.75 Gy of silicon ions. White spots were found in the mid-ventrum and tail-tips of irradiated offspring. The frequency and size of the white spots in the mid-ventrum in mice exposed to silicon, argon and iron ions were greater than those of gamma-rays. Even in the low dose (0.1 Gy), gamma-rays and heavy ions increased the frequency of the ventral spots. The RBE estimated by the frequency of the ventral spots was 2.3 (Si), 3.1 (Ar) and 4.5 (Fe). These results suggest that prenatal exposure to heavy ions possesses a greater effect on the postnatal development of mice as well as melanocyte development than does exposure to gamma-rays.","subitem_description_type":"Abstract"}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1269/jrr.10140","subitem_relation_type_select":"DOI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0449-3060","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hirobe, Tomohisa"}],"nameIdentifiers":[{"nameIdentifier":"458789","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Eguchi-Kasai, Kiyomi"}],"nameIdentifiers":[{"nameIdentifier":"458790","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sugaya, Kimihiko"}],"nameIdentifiers":[{"nameIdentifier":"458791","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Murakami, Masahiro"}],"nameIdentifiers":[{"nameIdentifier":"458792","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"廣部 知久","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"458793","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"笠井 清美","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"458794","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"菅谷 公彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"458795","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"村上 正弘","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"458796","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Effects of Low-dose Heavy Ions on the Postnatal Development of Mice and the Yield of White Spots in the Mid-ventrum and Tail-tips","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effects of Low-dose Heavy Ions on the Postnatal Development of Mice and the Yield of White Spots in the Mid-ventrum and Tail-tips"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-06-02"},"publish_date":"2011-06-02","publish_status":"0","recid":"46087","relation_version_is_last":true,"title":["Effects of Low-dose Heavy Ions on the Postnatal Development of Mice and the Yield of White Spots in the Mid-ventrum and Tail-tips"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:56:01.536678+00:00"}