{"created":"2023-05-15T14:35:47.611205+00:00","id":46046,"links":{},"metadata":{"_buckets":{"deposit":"0f0ca51e-6fd1-4833-979a-0c9d93d3ff39"},"_deposit":{"created_by":1,"id":"46046","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"46046"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00046046","sets":["1"]},"author_link":["458349","458345","458352","458347","458351","458346","458350","458348"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-04","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"8","bibliographicPageEnd":"2440","bibliographicPageStart":"2437","bibliographicVolumeNumber":"21","bibliographic_titles":[{"bibliographic_title":"Bioorganic & Medicinal Chemistry Letters"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We describe the synthesis of 11C-labeled a-aminoisobutyric acid 2 from iodo[11C]methane and methyl N-(diphenylmethylen)-D,L-alaniate (5). The tetrabutylammonium fluoride (TBAF)-promoted a-[11C]methylation of sterically hindered analog 5 was a key step in our synthesis process. Total radiochemical conversion of 2 was high and a remote-controlled synthesis was carried out. A comparative tumor positron emission tomography (PET) imaging study using the same model mouse showed higher uptake of 2 than with 11C-labeled methionine and [18F] fluorodeoxyglucose (FDG).","subitem_description_type":"Abstract"}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0960-894X","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kato, Koichi"}],"nameIdentifiers":[{"nameIdentifier":"458345","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsuji, Atsushi"}],"nameIdentifiers":[{"nameIdentifier":"458346","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Saga, Tsuneo"}],"nameIdentifiers":[{"nameIdentifier":"458347","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Zhang, Ming-Rong"}],"nameIdentifiers":[{"nameIdentifier":"458348","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"加藤 孝一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"458349","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"辻 厚至","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"458350","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐賀 恒夫","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"458351","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"張 明栄","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"458352","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"An efficient and expedient method for the synthesis of 11C-labeled a-aminoisobutyric acid: A tumor imaging agent potentially useful for cancer diagnosis","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"An efficient and expedient method for the synthesis of 11C-labeled a-aminoisobutyric acid: A tumor imaging agent potentially useful for cancer diagnosis"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-05-23"},"publish_date":"2011-05-23","publish_status":"0","recid":"46046","relation_version_is_last":true,"title":["An efficient and expedient method for the synthesis of 11C-labeled a-aminoisobutyric acid: A tumor imaging agent potentially useful for cancer diagnosis"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:56:30.460364+00:00"}