@article{oai:repo.qst.go.jp:00046018,
 author = {Kato, Koichi and Zhang, Ming-Rong and Minegishi, Katsuyuki and Nengaki, Nobuki and Takei, Makoto and Suzuki, Kazutoshi and 加藤 孝一 and 張 明栄 and 峯岸 克行 and 念垣 信樹 and 武井 誠 and 鈴木 和年},
 issue = {3},
 journal = {Journal of Labelled Compounds & Radiopharmaceuticals},
 month = {Mar},
 note = {The nitroaldol reaction of nitro[11C]methane and formaldehyde, which yields 2-(hydroxymethyl)-2-nitro[2-11C]propane-1,3-diol, is explored. The fluoride-ion-assisted nitroaldol reaction using (C4H9)4NF was rapid and provided the desired nitrotriol in more than 97% radiochemical conversion (decay-corrected) in 3 min at room temperature. Neither 2-nitro[2-11C]ethanol nor 2-nitro[2-11C]propane-1,3-diol was observed under the reaction conditions. The preparation of 2-amino-2-(hydroxymethyl)-[2-11C]propane-1,3-diol ([11C]Tris) was described, which was followed by the nitro-group reduction using NiCl2 and NaBH4 in aqueous MeOH. The decay-corrected radiochemical conversion to [11C]Tris was 68.0+/-6.5% in two steps.},
 pages = {140--144},
 title = {Nitroaldol reaction of nitro[11C]methane to form 2-(hydroxymethyl)-2-nitro[2-11C]-propane-1,3-diol and [11C]Tris},
 volume = {54},
 year = {2011}
}