@article{oai:repo.qst.go.jp:00045995,
 author = {Okada, Tohru and Kamada, Tadashi and Tsuji, Hiroshi and Mizoe, Junetsu and Baba, Masayuki and Kato, Shingo and Yamada, Shigeru and Sugahara, Shinji and Yasuda, Shigeo and Yamamoto, Naoyoshi and Imai, Reiko and Hasegawa, Azusa and Imada, Hiroshi and Kiyohara, Hiroki and Jingu, Keiichi and Shinoto, Makoto and Tsujii, Hirohiko and 岡田 徹 and 鎌田 正 and 辻 比呂志 and 溝江 純悦 and 馬場 雅行 and 加藤 眞吾 and 山田 滋 and 菅原 信二 and 安田 茂雄 and 山本 直敬 and 今井 礼子 and 長谷川 安都佐 and 今田 浩史 and 清原 浩樹 and 神宮 啓一 and 篠藤 誠 and 辻井 博彦},
 issue = {4},
 journal = {Journal of Radiation Research},
 month = {Jul},
 note = {In June 1994, the world's first clinical center offering carbon ion radiotherapy opened at the National Institute of Radiological Science (NIRS), Japan. Among several types of ion species, carbon ions were chosen for cancer therapy because they were judged to have the most optimal properties in terms of superior physical and biological characteristics. As of March 2010, 5,196 patients have been registered for carbon ion radiotherapy. Clinical results have shown that carbon ion radiotherapy has the potential to provide a sufficient radiation dose to the tumor, while having acceptable morbidity in the surrounding normal tissues. Tumors that appear to respond favorably to carbon ions include locally advanced tumors as well as histologically non-squamous cell tumor types such as adenocarcinoma, adenoid cystic carcinoma, malignant melanoma, hepatoma, and bone/soft tissue sarcoma. By taking advantage of the unique properties of carbon ions, treatment with small fractions within a short treatment period has been successfully carried out for a variety of tumors. This means that carbon ion radiotherapy can offer treatment for larger numbers of patients than is possible with other modalities over the same time period.},
 pages = {355--364},
 title = {Carbon Ion Radiotherapy:  Clinical Experiences at National Institute of Radiological Sciences (NIRS)},
 volume = {51},
 year = {2010}
}