{"created":"2023-05-15T14:35:44.325412+00:00","id":45971,"links":{},"metadata":{"_buckets":{"deposit":"2010d9cf-00d4-4bd8-a467-2814c0beb175"},"_deposit":{"created_by":1,"id":"45971","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"45971"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00045971","sets":["1"]},"author_link":["457416","457421","457415","457417","457420","457419","457418"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-02","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"401","bibliographicPageStart":"395","bibliographicVolumeNumber":"57","bibliographic_titles":[{"bibliographic_title":"Endocrine Journal"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"As  18F-fluorodeoxyglucose  (FDG)  positron  emission  tomography  (PET)  is  becoming  a  common  imaging \nmodality, the number of thyroid incidentalomas identified by FDG-PET (PET incidentaloma) is increasing.  The purpose \nof this study was to elucidate the risk of cancer in focal thyroid PET incidentaloma in healthy subjects of relatively younger \nage as well as the usefulness of repeated FDG-PET.  The study was conducted with an observation period of three years.  \nA total of 1,501 healthy volunteers (mean age, 43.5+/-9.7 years) underwent the first FDG-PET from August 2003 to July \n2004.  When focal thyroid PET incidentaloma was found, further diagnostic examination was conducted.  When thyroid \ncancer was suspected, surgical resection was performed with the patient's agreement.  Patients with PET incidentaloma \nwithout surgery were offered annual US and FDG-PET and finally FNAB was performed in the fourth year.  Focal thyroid \nPET incidentaloma was observed in 20 subjects.  The final diagnoses in 20 subjects were malignant in 11 (ten papillary \nthyroid  carcinoma  (PTC)  and  one  thyroid  carcinoma  showing  thymus-like  differentiation),  indeterminate  in  one,  and \nbenign in eight subjects.  Seven patients not treated surgically at the first examination had annual FDG-PET.  One patient \nwith PTC showed increasing SUVmax, but another with a benign nodule exhibited a similar increase.  Others (one with \nPTC, one with an indeterminate nodule, and three with benign nodules) exhibited negligible SUVmax changes.  When \nclosely examined, focal thyroid PET incidentaloma in relatively young healthy adults has a high probability of malignancy.  \nRepeated FDG-PET to follow up patients with thyroid nodules is ineffective.","subitem_description_type":"Abstract"}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1507/endocrj. k10e-008","subitem_relation_type_select":"DOI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0918-8959","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ohba, Kenji"}],"nameIdentifiers":[{"nameIdentifier":"457415","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nishizawa, Sadahiko"}],"nameIdentifiers":[{"nameIdentifier":"457416","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Inubushi, Masayuki"}],"nameIdentifiers":[{"nameIdentifier":"457417","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Okada, Hiroyuki"}],"nameIdentifiers":[{"nameIdentifier":"457418","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nakamura, Hirotoshi"}],"nameIdentifiers":[{"nameIdentifier":"457419","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"et.al"}],"nameIdentifiers":[{"nameIdentifier":"457420","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"犬伏 正幸","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"457421","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"High incidence of thyroid cancer in focal thyroid incidentaloma detected by 18F-fluorodexyglucose positron emission tomography in relatively young healthy subjects: results of 3-year follow-up.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"High incidence of thyroid cancer in focal thyroid incidentaloma detected by 18F-fluorodexyglucose positron emission tomography in relatively young healthy subjects: results of 3-year follow-up."}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-12-21"},"publish_date":"2010-12-21","publish_status":"0","recid":"45971","relation_version_is_last":true,"title":["High incidence of thyroid cancer in focal thyroid incidentaloma detected by 18F-fluorodexyglucose positron emission tomography in relatively young healthy subjects: results of 3-year follow-up."],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:57:25.238548+00:00"}