{"created":"2023-05-15T14:35:40.641827+00:00","id":45886,"links":{},"metadata":{"_buckets":{"deposit":"36a169df-ea1e-48f0-a41b-998e27bb9926"},"_deposit":{"created_by":1,"id":"45886","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"45886"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00045886","sets":["1"]},"author_link":["456406","456425","456407","456410","456415","456420","456417","456430","456431","456419","456408","456424","456428","456414","456426","456422","456423","456409","456416","456412","456411","456418","456429","456421","456413","456427"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-04","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"127","bibliographicPageEnd":"127-10","bibliographicPageStart":"127-1","bibliographicVolumeNumber":"10","bibliographic_titles":[{"bibliographic_title":"BMC Cancer (Online only:URL:http://www.biomedcentral.com/bmccancer)"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background\nTo evaluate the safety of focal dose escalation to regions with standardized uptake value (SUV) >2.0 using intensity-modulated radiation therapy (IMRT) by comparison of radiotherapy plans using dose-volume histograms (DVHs) and normal tissue complication probability (NTCP) for postoperative local recurrent rectal cancer\n\\nMethods\nFirst, we performed conventional radiotherapy with 40 Gy/20 fr. (CRT 40 Gy) for 12 patients with postoperative local recurrent rectal cancer, and then we performed FDG-PET/CT radiotherapy planning for those patients. We defined the regions with SUV > 2.0 as biological target volume (BTV) and made three boost plans for each patient: 1) CRT boost plan, 2) IMRT without dose-painting boost plan, and 3) IMRT with dose-painting boost plan. The total boost dose was 20 Gy. In IMRT with dose-painting boost plan, we increased the dose for BTV+5 mm by 30% of the prescribed dose. We added CRT boost plan to CRT 40 Gy (summed plan 1), IMRT without dose-painting boost plan to CRT 40 Gy (summed plan 2) and IMRT with dose-painting boost plan to CRT 40 Gy (summed plan 3), and we compared those plans using DVHs and NTCP.\n\\nResults\nDmean of PTV-PET and that of PTV-CT were 26.5 Gy and 21.3 Gy, respectively. V50 of small bowel PRV in summed plan 1 was significantly higher than those in other plans ((summed plan 1 vs. summed plan 2 vs. summed plan 3: 47.11 +/- 45.33 cm3 vs. 40.63 +/- 39.13 cm3 vs. 41.25 +/- 39.96 cm3(p < 0.01, respectively)). There were no significant differences in V30, V40, V60, Dmean or NTCP of small bowel PRV.\n\\nConclusions\nFDG-PET-guided IMRT can facilitate focal dose-escalation to regions with SUV above 2.0 for postoperative local recurrent rectal cancer.","subitem_description_type":"Abstract"}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1186/1471-2407-10-127","subitem_relation_type_select":"DOI"}}]},"item_8_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"http://www.biomedcentral.com/1471-2407/10/127"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.biomedcentral.com/1471-2407/10/127","subitem_relation_type_select":"URI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1471-2407","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Jingu, Keiichi"}],"nameIdentifiers":[{"nameIdentifier":"456406","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ariga, Hisanori"}],"nameIdentifiers":[{"nameIdentifier":"456407","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kaneta, Tomohiro"}],"nameIdentifiers":[{"nameIdentifier":"456408","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takai, Yoshihiro"}],"nameIdentifiers":[{"nameIdentifier":"456409","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takeda, Ken"}],"nameIdentifiers":[{"nameIdentifier":"456410","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Narazaki, Kakutarou"}],"nameIdentifiers":[{"nameIdentifier":"456411","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Metoki, Takahiro"}],"nameIdentifiers":[{"nameIdentifier":"456412","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fujimoto, Keisuke"}],"nameIdentifiers":[{"nameIdentifier":"456413","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Umezawa, Rei"}],"nameIdentifiers":[{"nameIdentifier":"456414","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ogawa, Yoshihiro"}],"nameIdentifiers":[{"nameIdentifier":"456415","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nemoto, Kenji"}],"nameIdentifiers":[{"nameIdentifier":"456416","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Koto, Masashi"}],"nameIdentifiers":[{"nameIdentifier":"456417","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mitsuya, Masatoshi"}],"nameIdentifiers":[{"nameIdentifier":"456418","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Matsufuji, Naruhiro"}],"nameIdentifiers":[{"nameIdentifier":"456419","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takahashi, Shoki"}],"nameIdentifiers":[{"nameIdentifier":"456420","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamada, Syougo"}],"nameIdentifiers":[{"nameIdentifier":"456421","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"et.al"}],"nameIdentifiers":[{"nameIdentifier":"456422","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"神宮 啓一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"456423","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"有賀 久哲","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"456424","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高井 良尋","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"456425","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"武田 賢","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"456426","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小川 芳弘","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"456427","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"根本 建二","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"456428","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小藤 昌志","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"456429","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"松藤 成弘","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"456430","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"山田 章吾","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"456431","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Focal dose escalation using FDG-PET-guided intensity-modulated radiation therapy boost for postoperative local recurrent rectal cancer: a planning study with comparison of DVH and NTCP","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Focal dose escalation using FDG-PET-guided intensity-modulated radiation therapy boost for postoperative local recurrent rectal cancer: a planning study with comparison of DVH and NTCP"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-09-06"},"publish_date":"2010-09-06","publish_status":"0","recid":"45886","relation_version_is_last":true,"title":["Focal dose escalation using FDG-PET-guided intensity-modulated radiation therapy boost for postoperative local recurrent rectal cancer: a planning study with comparison of DVH and NTCP"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:58:25.020474+00:00"}