{"created":"2023-05-15T14:35:38.060397+00:00","id":45827,"links":{},"metadata":{"_buckets":{"deposit":"1fa90c84-974e-4388-896b-db6b24848026"},"_deposit":{"created_by":1,"id":"45827","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"45827"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00045827","sets":["1"]},"author_link":["455690","455688","455694","455687","455693","455692","455691","455689"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-09","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"9","bibliographicPageEnd":"1055","bibliographicPageStart":"1053","bibliographicVolumeNumber":"80","bibliographic_titles":[{"bibliographic_title":"Journal of Neurology, Neurosurgery, and Psychiatry"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"BACKGROUND: Pure autonomic failure (PAF) is a selective peripheral disorder in which Lewy bodies form within the autonomic ganglia. Patients with this disorder usually have no central lesions; however, chronic autonomic failure may secondarily affect the central nervous system. This study evaluated brain perfusion in patients with PAF by using N-isopropyl-p-(123)I iodoamphetamine ((123)I-IMP) single photon emission computed tomography (SPECT). METHODS: Six patients with PAF (all men; mean (SD) age 68+/-5 years) who had experienced autonomic symptoms for more than 5 years and six age-matched healthy control subjects (all men; mean (SD) age 67+/-5 years) were included in this study. The regions of interest (ROI) on spacially normalized (123)I-IMP SPECT images were automatically computed for both groups. RESULTS: Perfusion of the dorsal anterior cingulate cortex was decreased in the PAF group compared with the healthy control group (0.93 vs 1.01; p<0.001). In the other brain regions measured, there was no significant difference in regional perfusion between the two groups. CONCLUSIONS: The dorsal anterior cingulate cortex is poorly perfused and may be functionally altered in patients with PAF. The reduced perfusion in such individuals may be a secondary change that results from chronic autonomic failure.","subitem_description_type":"Abstract"}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0022-3050","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hirano, Shigeki"}],"nameIdentifiers":[{"nameIdentifier":"455687","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shimada, Hitoshi"}],"nameIdentifiers":[{"nameIdentifier":"455688","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shinoto, Hitoshi"}],"nameIdentifiers":[{"nameIdentifier":"455689","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hattori, Takamichi"}],"nameIdentifiers":[{"nameIdentifier":"455690","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"et.al"}],"nameIdentifiers":[{"nameIdentifier":"455691","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"平野 成樹","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"455692","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"島田 斉","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"455693","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"篠遠 仁","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"455694","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Reduced perfusion in the anterior cingulate cortex of patients with pure autonomic failure: an 123 I-IMP SPECT study","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Reduced perfusion in the anterior cingulate cortex of patients with pure autonomic failure: an 123 I-IMP SPECT study"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-06-17"},"publish_date":"2010-06-17","publish_status":"0","recid":"45827","relation_version_is_last":true,"title":["Reduced perfusion in the anterior cingulate cortex of patients with pure autonomic failure: an 123 I-IMP SPECT study"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:59:08.024267+00:00"}