{"created":"2023-05-15T14:35:37.500446+00:00","id":45814,"links":{},"metadata":{"_buckets":{"deposit":"623ba29b-36da-4e11-99aa-8938a39d85cb"},"_deposit":{"created_by":1,"id":"45814","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"45814"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00045814","sets":["1"]},"author_link":["455542","455541","455544","455543","455537","455539","455540","455538"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-07","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"836","bibliographicPageStart":"831","bibliographicVolumeNumber":"74","bibliographic_titles":[{"bibliographic_title":"International Journal of Radiation Oncology Biology Physics"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"PURPOSE: To evaluate the efficacy and safety of hypofractionated proton beam therapy for patients with hepatocellular carcinoma (HCC). METHODS AND MATERIALS: Between September 2001 and August 2004, 51 patients with HCC greater than 2 cm away from the porta hepatis or gastrointestinal tract were treated with proton beam therapy to 66 Gy-equivalents (GyE) in 10 fractions. RESULTS: Overall survival rates were 49.2 and 38.7% at 3 and 5 years after treatment. Local control rates were 94.5 and 87.8% at 3 and 5 years after treatment. Posttreatment serum alpha-fetoprotein values were significantly reduced when compared with pretreatment values (p < 0.0001). Patients experienced only minor acute reactions of Grade 1 or less, and 3 patients experienced late sequelae of Grade 2 or higher. However, there were no treatment-related deaths. CONCLUSIONS: Hypofractionated proton beam therapy is safe and well-tolerated by patients with HCC located greater than 2 cm away from the porta hepatis or gastrointestinal tract and may be effective alternative to other modalities.","subitem_description_type":"Abstract"}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0360-3016","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Fukumitsu, Nobuyoshi"}],"nameIdentifiers":[{"nameIdentifier":"455537","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sugahara, Shinji"}],"nameIdentifiers":[{"nameIdentifier":"455538","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nakayama, Hidetsugu"}],"nameIdentifiers":[{"nameIdentifier":"455539","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsuboi, Koji"}],"nameIdentifiers":[{"nameIdentifier":"455540","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"et.al"}],"nameIdentifiers":[{"nameIdentifier":"455541","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"菅原 信二","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"455542","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中山 秀次","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"455543","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"坪井 康次","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"455544","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"A Prospective Study of Hypofractionated Proton Beam Therapy for Patients with Hepatocellular Carcinoma","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"A Prospective Study of Hypofractionated Proton Beam Therapy for Patients with Hepatocellular Carcinoma"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-06-16"},"publish_date":"2010-06-16","publish_status":"0","recid":"45814","relation_version_is_last":true,"title":["A Prospective Study of Hypofractionated Proton Beam Therapy for Patients with Hepatocellular Carcinoma"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T23:59:17.061854+00:00"}