@article{oai:repo.qst.go.jp:00045799,
 author = {Fujii, Yoshihiro and Kato, Takamitsu and Ueno, Akiko and Kubota, Nobuo and Fujimori, Akira and Okayasu, Ryuichi and 藤井 義大 and 加藤 宝光 and 上野 昭子 and 窪田 宜夫 and 藤森 亮 and 岡安 隆一},
 issue = {1/2},
 journal = {Genetic Toxicology and Environmental Mutagenesis : A Section of Mutation Research},
 month = {Jun},
 note = {We studied the effects and mechanisms of ascorbic acid as a radiation protector. Cell survival, repair of DNA double strand breaks (DSBs), and sister chromatid exchanges (SCEs) were examined in normal human fibroblasts irradiated with X-rays and heavy ions. Post irradiation treatment with 5 mM ascorbic acid for 24 hours in plateau phase (non-cycling) cells enhanced cell survival and DNA double strand break repair, and reduced SCEs after X-rays irradiation. On the other hand, only reduced SCEs were observed after heavy ion exposure such as to carbon ions. 
Judging from our data, it is possible that the radioprotective action of ascorbic acid would be effective in non-complex type DNA damage such as induced by X-rays.  These findings provide new insight into the mechanism of DNA damage and repair produced by heavy ion irradiation.},
 pages = {58--61},
 title = {Ascorbic acid gives different protective effects in human cells exposed to X-rays and heavy ions},
 volume = {699},
 year = {2010}
}