@article{oai:repo.qst.go.jp:00045788,
 author = {Goudarzi, Behnaz and Kishimoto, Riwa and Komatu, Syuhei and Ishikawa, Hiroyuki and Yoshikawa, Kyosan and Kandatsu, Susumu and Obata, Takayuki and Ｇｏｕｄａｒｚｉ Ｂｅｈｎａｚ and 岸本 理和 and 小松 秀平 and 石川 博之 and 吉川 京燦 and 神立 進 and 小畠 隆行},
 issue = {3},
 journal = {Magnetic Resonance Imaging},
 month = {Jan},
 note = {Purpose: We evaluated the ability of diffusion-weighted imaging (DWI) to detect bone metastasis by comparing the results obtained using this modality with those obtained using 11C-methionine (MET) positron emission tomography (PET) and bone scintigraphy.
Materials and methods: This retrospective study involved 29 patients with bone metastasis. DWI was obtained using a single-shot echo planar imaging (EPI) sequence with fat suppression using a short inversion time inversion recovery sequence. The detection capabilities of DWI for bone metastases were compared with those of whole body MET PET (in 19 patients) and 99mTc-methylene diphosphonate bone scintigraphy (in 15 patients).
Results: Among the 19 patients who were diagnosed using DWI and PET,the PET identified 39 bone metastases, while the DWI identified 60 metastases out of 69 metastases revealed with conventional magnetic resonance imaging (MRI).Among the 15 patients who were diagnosed using DWI and bone scintigraphy,the bone scintigraphy identified 18 bone metastases, while the DWI identified 72 metastases out of 78 metastases revealed with conventional MRI. The overall bone metastasis detection rates were 56.5% for PET, 23.1% for bone scintigraphy and 92.3% for DWI.
Conclusion: DWI is a very sensitive method for detecting bone metastasis and is superior to MET PET and bone scintigraphy in terms of its detection capabilities.},
 pages = {372--379},
 title = {Detection of bone metastases using diffusion weighted magnetic resonance imaging: comparison with 11C-methionine PET and bone scintigraphy},
 volume = {28},
 year = {2010}
}