@article{oai:repo.qst.go.jp:00045549, author = {Yoshida, Eiji and Kitamura, Keishi and Nishikido, Fumihiko and Shibuya, Kengo and Hasegawa, Tomoyuki and Yamaya, Taiga and Inadama, Naoko and Murayama, Hideo and 吉田 英治 and 北村 圭司 and 錦戸 文彦 and 澁谷 憲悟 and 長谷川 智之 and 山谷 泰賀 and 稲玉 直子 and 村山 秀雄}, issue = {1/2}, journal = {Nuclear Instruments & Methods in Physics Research Section A}, month = {Jan}, note = {Conventionally, positron emission tomograph (PET) scanners use scintillators which have a high effective atomic number. Recently, novel scintillators like LaBr3 have been developed which have excellent timing and energy resolutions. LaBr3 has a high performance for PET scanner use, but its effective atomic number is lower than that of lutetium oxyorthosilicate (LSO). As an alternative, we have developed a scatter reduction method using depth-of-interaction (DOI) information and energy information to increase the sensitivity. The sensitivity of the PET scanner with LaBr3 can be improved using the DOI-dependent extended-energy window (DEEW) method. In this work, our method is applied to the whole-body LSO/LaBr3 PET scanner using the GATE simulation toolkit. Simulation results show the number of true coincidences can be increased while minimizing the scatter and random coincidences by using the DEEW method. Noise equivalent count rate (NECR) can be improved by 20–70% for the whole-body DOI-PET scanner. Sensitivity of the PET scanner with a scintillator of low-effective atomic number can be improved by the DEEW method.}, pages = {363--365}, title = {Feasibility study of a highly sensitive LaBr3 PET scanner based on the DOI-dependent extended-energy window}, volume = {604}, year = {2009} }