@article{oai:repo.qst.go.jp:00045537, author = {Tomiyasu, Moyoko and Obata, Takayuki and Nonaka, Hiroi and Nishi, Yukio and Nakamoto, Hiromitsu and Takayama, Yukihisa and Ikehira, Hiroo and Kanno, Iwao and 富安 もよこ and 小畠 隆行 and 野中 博意 and 西 幸雄 and 中本 泰充 and 高山 幸久 and 池平 博夫 and 菅野 巖}, issue = {4}, journal = {Magnetic Resonance Imaging}, month = {Feb}, note = {To evaluate the contamination of glycogen signal synthesized in skeletal muscle by that in the liver, long-term monitoring of over 7 h of in vivo [1-13C] glycogen synthesis/degradation at the right abdomen and left shoulder was achieved using a 3.0-T clinical MR system. 13C MR spectra without localization were obtained from five healthy volunteers before and after oral administration of 85 g of D-glucose, including 10 g of 99% [1-13C] glucose. In all volunteers, the relative signal intensities at the abdomen to those at shoulder were about two- to fivefold, and those of time-course changes at the abdomen and shoulder were dissimilar. It is considered that the quantity of muscle-synthesized glycogen signal at the abdomen is less than that at the shoulder because of the lesser muscle volume at the abdomen, and it may be less affected for evaluating glycogen synthesis/degradation in the liver even without localization pulses.}, pages = {572--576}, title = {Evaluating glycogen signal contamination in muscle by 13C MRS of the liver}, volume = {26}, year = {2008} }