@article{oai:repo.qst.go.jp:00045502, author = {Takeda, Hiroshi and Fuma, Shoichi and Miyamoto, Kiriko and Yanagisawa, Kei and Ishii, Nobuyoshi and Kawaguchi, Isao and Doi, Kazutaka and Melintescu, Anca and Galeriu, Dan and 武田 洋 and 府馬 正一 and 宮本 霧子 and 柳澤 啓 and 石井 伸昌 and 川口 勇生 and 土居 主尚}, issue = {5}, journal = {Health Physics}, month = {May}, note = {Biokinetics of radiocarbon (14C) in rats during 14 weeks continuous ingestion of 14C-wheat was investigated to obtain the dosimetric data on organic 14C ingested as a food. After the start of continuous ingestion of 14C-wheat, the concentrations of 14C in both wet and dry tissues gradually increased and showed a tendency to became a steady-state condition for the most of tissues except adipose tissue within the continuous ingestion. The steady-state condition was observed at 10 weeks in the majority of tissues, but it was at 3 weeks in liver. The steady-state concentrations in wet tissues ranged from about 10 % to 40 % and those in dry tissues ranged from about 80 % to 100 % of the concentration of 14C in the ingested food. The highest steady-state concentrations in both wet and dry tissues were observed in liver. When compared the concentrations among tissues at the end of 14 weeks continuous ingestion, adipose tissue was the highest in wet tissue and the lowest in dry tissue. From the concentrations of 14C in wet tissues at the 14th week, the radiation dose rates to individual tissues were estimated. The dose rates were different among the tissues. The highest dose rate was observed in adipose tissue. The next highest dose rates were found in liver and small intestine, while lower doses were measured in testis and lung. The differences in the dose rate among the tissues seemed to be mainly dependent on the variation in the organic content of each tissue.}, pages = {587--593}, title = {BIOKINETICS OF RADIOCARBON INGESTED AS A FOOD IN RATS}, volume = {96}, year = {2009} }