@article{oai:repo.qst.go.jp:00045309, author = {Sakai, Yuji and Nonaka, Hiroi and Ikehira, Hiroo and Obata, Takayuki and Miyazaki, Masaru and et.al and 酒井 裕司 and 野中 博意 and 池平 博夫 and 小畠 隆行 and 宮崎 勝}, issue = {81}, journal = {Hepato-Gastroenterology}, month = {Jan}, note = {Background/Aims: The aim of this study was to investigate whether exogenous dehydrocholic acid (DHCA) was useful to enhance the delineation of anastomotic site. Methodology: DHCA is a cholagogue which produces an immediate effect by acting directly on liver cells. Its choleretic effect is strong, appearing 1 to 3 minutes after intravenous injection, reaching the maximum level in 20 to 30 minutes. Our study population comprised 9 patients. Magnetic resonance cholangiopancreatography (MRCP) was acquired before and after the administration of DHCA. Two different MRCP snap-shot techniques were applied: thick-slab two-dimensional (2D) (coronal) singleshot turbo spin echo T2-weighted sequences and multisection thin-slab, 2D (coronal) single shot turbo spin echo T2-weighted sequences with threedimensional (3D) maximum intensity projection (MIP) post processing. Results: DHCA provided a better visualization of the anastomotic site in 7 patients (77.8%). The two patients without improvement in visualization of anastomotic site included 1 patient with liver cirrhosis secondary to portoenterostomy for ongenital biliary dilatation and 1 patient, who was not eligible for the evaluation because of motion artifact caused by the difficulty of breath holding motion artifact. Conclusions: It was suggested that administration of DHCA could enhance the elineation of the anastomotic site on MRCP images.}, pages = {17--20}, title = {Magnetic resonance cholangiopancreatography: potential usefulness of dehydrocholic acid (DHCA) administration in the evaluation of anastomotic site}, volume = {55}, year = {2008} }