{"created":"2023-05-15T14:35:04.026870+00:00","id":45271,"links":{},"metadata":{"_buckets":{"deposit":"1caa5c66-3dcc-40c9-bcd6-38f0a8f4c113"},"_deposit":{"created_by":1,"id":"45271","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"45271"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00045271","sets":["1"]},"author_link":["449702","449704","449707","449701","449703","449709","449698","449710","449705","449700","449708","449706","449699"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-11","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"9","bibliographicPageEnd":"535","bibliographicPageStart":"533","bibliographicVolumeNumber":"21","bibliographic_titles":[{"bibliographic_title":"Annals of Nuclear Medicine"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The applicability of total distribution volume (DVt) as an alternative to binding potential (BP) was investigated for neuroreceptor mapping by positron emission tomography (PET). BP is defi ned as a representative quantity of receptor density. However, for making parametric images of BP, a reference region where an aimed receptor has a very low density is assumed to exist in a target region such as the brain. Thus, if the kinetics of a radioligand for target receptors does not permit an appropriate reference region, BP imaging is unattainable. In this study, [11C]SA4503 PET is taken to be considered which has a high affi nity to the sigma1 receptors. Through a clinical investigation using wide ranges of physiological situations, ages, sex, diseases, and selective drug-loading conditions, DVt has a\ngood linear relationship with BP, and the images can be used as a spatial stribution of sigma1 density.","subitem_description_type":"Abstract"}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1007/s12149-007-0063-6","subitem_relation_type_select":"DOI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0914-7187","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kimura, Yuichi"}],"nameIdentifiers":[{"nameIdentifier":"449698","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Naganawa, Mika"}],"nameIdentifiers":[{"nameIdentifier":"449699","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sakata, Muneyuki"}],"nameIdentifiers":[{"nameIdentifier":"449700","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ishikawa, Masatomo"}],"nameIdentifiers":[{"nameIdentifier":"449701","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mishina, Masahiro"}],"nameIdentifiers":[{"nameIdentifier":"449702","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Oda, Keiichi"}],"nameIdentifiers":[{"nameIdentifier":"449703","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ishii, Kenji"}],"nameIdentifiers":[{"nameIdentifier":"449704","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ishiwata, Kiichi"}],"nameIdentifiers":[{"nameIdentifier":"449705","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"木村 裕一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"449706","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"長縄 美香","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"449707","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"織田 圭一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"449708","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石井 賢二","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"449709","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石渡 喜一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"449710","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Distribution volume as an alternative to the binding potential for sigma1receptor imaging","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Distribution volume as an alternative to the binding potential for sigma1receptor imaging"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-09-22"},"publish_date":"2008-09-22","publish_status":"0","recid":"45271","relation_version_is_last":true,"title":["Distribution volume as an alternative to the binding potential for sigma1receptor imaging"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-16T00:05:42.821763+00:00"}