@article{oai:repo.qst.go.jp:00045245, author = {Zhang, Wei and Chun, Yan Wang and Minamihisamatsu, Masako and Luxin, Wei and Sugahara, Tsutomu and Hayata, Isamu and 張 偉 and 王 春燕 and 南久松 眞子 and 早田 勇}, issue = {1}, journal = {Genetic Toxicology and Environmental Mutagenesis : A Section of Mutation Research}, month = {May}, note = {To clarify the low-dose limit at which the effect of radiation on health becomes undetectable is important in the regulation of radiation. As one of a series of cytogenetical studies on the effect of radiation on health, we present low-dose limits determined by analyzing the background frequencies of translocations in the lymphocytes of people living in normal circumstances. The frequencies of translocations in the lymphocytes were analyzed in 20 non-smokers (61.2-year-old on the average) in a large city, and 16 non-smokers (64.4-year-old on the average) and 8 children (12.3-year-old on the average) in a remote village. The radiation dose was calculated based on the background frequencies of translocations assuming that all the translocations had been induced by radiation. The calculated doses were 384+/- 200, 336+/-124 and 128+/- 80 mSv in the case of chronic exposure, and 248 +/- 153, 225 +/- 104 and 107 +/- 72 mSv in acute exposure. Standard deviation of the calculated doses is considered to be the dose level below which the effect of radiation becomes undetectable due to the background variation in the effects of all kind of mutagenic factors, i.e., the dose level below which an epidemiological study will not be able to show any significant increase in malignant diseases. The results obtained from epidemiological study will not be able to show any significant increase in malignant diseases. The results obtained from epidemiological studies are in fairly good agreement with our results.}, pages = {96--99}, title = {Dose limits below which the effect of radiation on health becomes undetectable due to background variation}, volume = {654}, year = {2008} }