@article{oai:repo.qst.go.jp:00045204,
 author = {Kase, Yuuki and Kanai, Tatsuaki and Matsufuji, Naruhiro and Furusawa, Yoshiya and et.al and 加瀬 優紀 and 金井 達明 and 松藤 成弘 and 古澤 佳也},
 issue = {1},
 journal = {Physics in Medicine and Biology},
 month = {Dec},
 note = {Both the microdosimetric kinetic model (MKM) and the local effect model
(LEM) can be used to calculate the surviving fraction of cells irradiated by
high-energy ion beams. In this study, amorphous track structuremodels instead
of the stochastic energy deposition are used for the MKM calculation, and it is
found that the MKM calculation is useful for predicting the survival curves of
the mammalian cells in vitro for 3He-, 12C- and 20Ne-ion beams. The survival
curves are also calculated by two different implementations of the LEM, which
inherently used an amorphous track structure model. The results calculated
in this manner show good agreement with the experimental results especially
for the modified LEM. These results are compared to those calculated by the
MKM. Comparison of the two models reveals that both models require three
basic constituents: target geometry, photon survival curve and track structure,
although the implementation of each model is significantly different. In the
context of the amorphous track structure model, the difference between the
MKM and LEM is primarily the result of different approaches calculating
the biological effects of the extremely high local dose in the center of the ion
track.},
 pages = {37--59},
 title = {Biophysical calculation of cell survival probabilities using amorphous track structure models for heavy-ion irradiation},
 volume = {53},
 year = {2007}
}