{"created":"2023-05-15T14:34:58.165201+00:00","id":45182,"links":{},"metadata":{"_buckets":{"deposit":"f04ac8a6-faa8-4c15-be25-35ce2ad8fd4d"},"_deposit":{"created_by":1,"id":"45182","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"45182"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00045182","sets":["1"]},"author_link":["448779","448785","448772","448777","448771","448770","448782","448776","448783","448784","448787","448780","448775","448786","448778","448781","448774","448773"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-05","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"10","bibliographicPageEnd":"e59-11","bibliographicPageStart":"e59-1","bibliographicVolumeNumber":"36","bibliographic_titles":[{"bibliographic_title":"Nucleic Acids Research"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Mammalian genomes contain numerous evolutionary harbored mobile elements, a part of which are still active and may cause genomic instability. Their movement and positional diversity occasionally result in phenotypic changes and variation by causing altered expression or disruption of neighboring host genes. Here, we describe a novel microarraybased method by which dispersed genomic locations\nof a type of retrotransposon in a mammalian genome can be identified. Using this method, we mapped the DNA elements for a mouse retrotransposon,\nintracisternal A-particle (IAP), within genomes of C3H/He and C57BL/6J inbred mouse strains; consequently we detected hundreds of probable IAP cDNA–integrated genomic regions, in which a considerable number of strain-specific putative insertions were included. In addition, by comparing genomic DNAs from radiation-induced myeloid leukemia cells and its reference normal tissue, we detected three genomic regions around which an IAP element was integrated. These results demonstrate the first successful genome-wide mapping of a retrotransposon type in a mammalian genome.","subitem_description_type":"Abstract"}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1093/nar/gkn235","subitem_relation_type_select":"DOI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0305-1048","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Takabatake, Takashi"}],"nameIdentifiers":[{"nameIdentifier":"448770","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ishihara, Hiroshi"}],"nameIdentifiers":[{"nameIdentifier":"448771","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ohmachi, Yasushi"}],"nameIdentifiers":[{"nameIdentifier":"448772","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tanaka, Izumi"}],"nameIdentifiers":[{"nameIdentifier":"448773","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"M., Nakamura Masako"}],"nameIdentifiers":[{"nameIdentifier":"448774","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fujikawa, Katsuyoshi"}],"nameIdentifiers":[{"nameIdentifier":"448775","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hirouchi, Tokuhisa"}],"nameIdentifiers":[{"nameIdentifier":"448776","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kakinuma, Shizuko"}],"nameIdentifiers":[{"nameIdentifier":"448777","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shimada, Yoshiya"}],"nameIdentifiers":[{"nameIdentifier":"448778","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Oghiso, Yoichi"}],"nameIdentifiers":[{"nameIdentifier":"448779","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tanaka, Kimio"}],"nameIdentifiers":[{"nameIdentifier":"448780","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高畠 貴志","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"448781","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石原 弘","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"448782","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"大町 康","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"448783","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田中 泉","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"448784","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"柿沼 志津子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"448785","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"島田 義也","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"448786","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田中 公夫","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"448787","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Microarray-based global mapping of integration sites for the retrotransposon, intracisternal A-particle, in the mouse genome","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Microarray-based global mapping of integration sites for the retrotransposon, intracisternal A-particle, in the mouse genome"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-06-10"},"publish_date":"2008-06-10","publish_status":"0","recid":"45182","relation_version_is_last":true,"title":["Microarray-based global mapping of integration sites for the retrotransposon, intracisternal A-particle, in the mouse genome"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-16T00:06:42.082226+00:00"}