{"created":"2023-05-15T14:34:46.556124+00:00","id":44952,"links":{},"metadata":{"_buckets":{"deposit":"50454ec1-90fb-49dc-b9fa-4d2c9e7d260e"},"_deposit":{"created_by":1,"id":"44952","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"44952"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00044952","sets":["1"]},"author_link":["446421","446424","446425","446420","446423","446422"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-05","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"11","bibliographicPageStart":"1","bibliographicVolumeNumber":"2","bibliographic_titles":[{"bibliographic_title":"Algorithms for Molecular Biology (Online only URL: http://www.almob.org/)"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background: One-dimensional (l-D) electrophoretic data obtained using the cDNA-AFLP method hava attracted great interest for the identification of differentially expressed transcript-derived fragments (TDFs).However,high-throughput analysis of the cDNA-AFLP data is currently limited by the need for labor-intensive visual evaluation of multiple electropherograms.We would like to hava high-throughput ways of identifying such TDFs.\n\\nResults:We describe a method,GOGOT,which automatically detects the differentially expressed TDFs in a set of time-course electropherograms.Analysis by GOGOT is conducted as follows:correction of fragment lengths of TDFs,alignment of identical TDFs across different electropherograms,normalization of peak heights,and identification of differentially expressed TDFs using a special atatistic.The output of the analysis is a highly reduced list of differentially expressed TDFs.Visual evaluation confirmed that the peak alignment was performed perfectly for the TDFs by virtue of the correction of peak fragment lengths before alignment in step l.The validity of the automated ranking of TDFs by the special statistic was confirmed by the visual evaluation of a third party.\n\\nConclusion:GOGOT is useful for the automated detection of differentially expressed TDFs from cDNA-AFLP temporal electrophoretic data.The current algorithm may be applied to other electrophoretic data and temporal microarray data.","subitem_description_type":"Abstract"}]},"item_8_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1186/1748-7188-2-5","subitem_relation_type_select":"DOI"}}]},"item_8_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"http://www.almob.org/content/2/1/5"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.almob.org/content/2/1/5","subitem_relation_type_select":"URI"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1748-7188","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kadota, Koji"}],"nameIdentifiers":[{"nameIdentifier":"446420","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Araki, Ryoko"}],"nameIdentifiers":[{"nameIdentifier":"446421","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nakai, Yuji"}],"nameIdentifiers":[{"nameIdentifier":"446422","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Abe, Masumi"}],"nameIdentifiers":[{"nameIdentifier":"446423","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"荒木 良子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"446424","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"安倍 真澄","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"446425","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"GOGOT: a method for the identification of differentially expressed fragments from cDNA-AFLP data","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"GOGOT: a method for the identification of differentially expressed fragments from cDNA-AFLP data"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2007-08-23"},"publish_date":"2007-08-23","publish_status":"0","recid":"44952","relation_version_is_last":true,"title":["GOGOT: a method for the identification of differentially expressed fragments from cDNA-AFLP data"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-16T00:09:24.785405+00:00"}