@article{oai:repo.qst.go.jp:00044925, author = {Bakalova-Zheleva, Rumiana and バカロバ ルミアナ}, issue = {1/3}, journal = {Brain Research Bulletin}, month = {Jun}, note = {To clarify the brain phenomena, to prove directly the major biochemical pathways in cerebral tissue, and to discover the crucial steps in brain pathology, it is necessary to develop a high speed deep-tissue imaging techniques with high spatial and temporal resolution, and ultra-fast and highly selective molecular sensors, giving a possibility to monitor target molecules directly in their physiological environment. This technical comment accents on the perspectives for development of direct approach for investigation of function/flow coupling phenomenon and zinc transport into the brain, based on the current progress in development of ultra-fast molecular sensors for direct visualization of biochemical mediators and neurotransmitters, and high speed multi-photon deep-tissue imaging.}, pages = {150--153}, title = {Fluorescent molecular sensors and multi-photon microscopy in brain studies}, volume = {73}, year = {2007} }