{"created":"2023-05-15T14:34:43.343905+00:00","id":44878,"links":{},"metadata":{"_buckets":{"deposit":"c135e784-a497-47ad-986f-7f631db9d9e2"},"_deposit":{"created_by":1,"id":"44878","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"44878"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00044878","sets":["1"]},"author_link":["445734","445736","445738","445733","445735","445737","445731","445739","445732","445740"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-4","bibliographicPageEnd":"194","bibliographicPageStart":"188","bibliographicVolumeNumber":"122","bibliographic_titles":[{"bibliographic_title":"Radiation Protection Dosimetry"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"This study aims to clarify the enhancement effect on chromosomal aberrations via selective energy absorption by Cu atoms incultured bone cancer cells with non-labelled Cu-pyruvaldehyde-bis(N4-methylsemicarbazone) (Cu-PTSM) and monochromatic X rays. The X rays having the energy of the Cu K-shell absorption edge arising from synchrotron radiation (KEK-PF) was used as radiation source. Cu-PTSM labeled with copper radionuclides has been developed for medical imaging using positron emission tomography (PET). Evidence clearly showed that the absorption of X rays in the Cu K-shell caused this enhancement. After cells were treated with 1000 nM Cu-PTSM, the enhancement ratio of the initial yield of isochromatid breaks caused by CuK-H X-ray irradiation to that by 200 kVp X rays was  2.8. About 5.6 times of the remaining isochromatid breaks were observed at 4 h in Cu-PTSM treated samples irradiated with CuK-H X rays comparing to thatwith 200 kVp X rays. In this study, uniqueness in physical property such as Cu atom K-shell ionisation was applied for the enhancement of biological effects in cancer cells.","subitem_description_type":"Abstract"}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0144-8420","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Takakura, Kaoru"}],"nameIdentifiers":[{"nameIdentifier":"445731","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yaguchi, Satoshi"}],"nameIdentifiers":[{"nameIdentifier":"445732","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kanasugi, Yuuichi"}],"nameIdentifiers":[{"nameIdentifier":"445733","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kobayashi, Katsumi"}],"nameIdentifiers":[{"nameIdentifier":"445734","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Okayasu, Ryuichi"}],"nameIdentifiers":[{"nameIdentifier":"445735","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fujibayashi, Yasuhisa"}],"nameIdentifiers":[{"nameIdentifier":"445736","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高倉 かほる","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"445737","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"金杉 勇一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"445738","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小林 克己","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"445739","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"岡安 隆一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"445740","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ENHANCEMENT OF CHROMOSOMAL ABERRATIONS IN  TUMOR CELLS WITH A NON-LABELED CU-PTSM AND IRRADIATION WITH CU K-SHELL MONOCHOROMATIC X RAYS","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ENHANCEMENT OF CHROMOSOMAL ABERRATIONS IN  TUMOR CELLS WITH A NON-LABELED CU-PTSM AND IRRADIATION WITH CU K-SHELL MONOCHOROMATIC X RAYS"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2007-06-13"},"publish_date":"2007-06-13","publish_status":"0","recid":"44878","relation_version_is_last":true,"title":["ENHANCEMENT OF CHROMOSOMAL ABERRATIONS IN  TUMOR CELLS WITH A NON-LABELED CU-PTSM AND IRRADIATION WITH CU K-SHELL MONOCHOROMATIC X RAYS"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-16T00:10:16.944058+00:00"}