@article{oai:repo.qst.go.jp:00044849,
 author = {Imaseki, Hitoshi and Ishikawa, Takahiro and Iso, Hiroyuki and Konishi, Teruaki and Suya, Noriyoshi and Hamano, Tsuyoshi and Wang, Xufei and Yasuda, Nakahiro and Yukawa, Masae and 今関 等 and 石川 剛弘 and 磯 浩之 and 小西 輝昭 and 酢屋 徳啓 and 濱野 毅 and 王 旭飛 and 安田 仲宏 and 湯川 雅枝},
 issue = {1},
 journal = {Nuclear Instruments & Methods in Physics Research Section B},
 month = {Feb},
 note = {At the National Institute of Radiological Sciences (NIRS), we constructed a microbeam system in 2003, the single particle irradiation to cell, SPICE. From the beginning of 2005, we redesigned it to improve the stability of the optical alignment of the system, and obtained an reduction of the beam size proportional to the vertical dimension of the object slits. As a result, SPICE is now capable of producing a beam size of approximately 10 lm diameter, and the particle numbers controllable to an intensity as low as single particles per second, and therefore a single particle irradiation facility has been successfully implemented. Moreover, these conditions can be easily reproduced with a employing a routine procedure. We describe in detail the modifications of the beam line and results, demonstrating the improvements. In addition, results from our first biological experiments are shown.},
 pages = {81--84},
 title = {Progress report of the single particle irradiation system to cell (SPICE)},
 volume = {260},
 year = {2007}
}