@article{oai:repo.qst.go.jp:00044788, author = {Mori, Shinichiro and Endo, Masahiro and Komatu, Syuhei and Kandatsu, Susumu and Yashiro, Tomoyasu and Baba, Masayuki and 森 慎一郎 and 遠藤 真広 and 小松 秀平 and 神立 進 and 矢代 智康 and 馬場 雅行}, issue = {16}, journal = {Physics in Medicine and Biology}, month = {Aug}, note = {The combination-weighted Feldkamp algorithm (CW-FDK) was developed and tested in a phantom in order to reduce cone beam artifacts and enhance cranio-caudal reconstruction coverage in an attempt to improve image quality when utilizing cone beam CT (CBCT). Using a 256-slice cone-beam CT (256CBCT), image quality (CT-number uniformity and geometrical accuracy) was quantitatively evaluated in phantom and clinical studies and the results were compared to those with the original Feldkamp algorithm. Clinical study was done in lung cancer patients under breath-holding and free breathing. Image quality for the original Feldkamp algorithm is degraded at the edge of the scan region due to the missing volume, commensurate with the cranio-caudal distance between the reconstruction and central planes. The CW-FDK extended the reconstruction coverage to equal the scan coverage and improved reconstruction accuracy, unaffected by cranio-caudal distance. The extended reconstruction coverage with good image quality provided by the CW-FDK will be clinically investigated for improving diagnostic and radiotherapy applications. In addition, this algorithm can also be adapted for use in relatively wide cone-angle CBCT such as with a flat-panel detector CBCT.}, pages = {3953--3965}, title = {A combination-weighted Feldkamp-based reconstruction algorithm for cone-beam CT}, volume = {51}, year = {2006} }