@article{oai:repo.qst.go.jp:00044734, author = {Araki, Ryoko and Fukumura, Ryuutarou and Sasaki, Naokazu and Kasama, Yasuji and Suzuki, Nobuko and Takahashi, Hirokazu and Tabata, Yoshimichi and Saito, Toshiyuki and Abe, Masumi and 荒木 良子 and 福村 龍太郎 and 佐々木 直一 and 笠間 康次 and 鈴木 展子 and 高橋 宏和 and 田端 義巌 and 齋藤 俊行 and 安倍 真澄}, issue = {11}, journal = {Stem Cells}, month = {Nov}, note = {To study the transcriptome of embryonic stem cells,we used a new gene expression profiling meethod which can measure the expression levels of unknown and rarely expressed transcripts precisely.We detected a total of 33,136 signal peaks representing transcripts in E14 mouse embryonic stem cells.Subsequent random cloning of the peaks suggests that mouse embryonic stem cells express at least 40,000 transcripts,of which about 2,000 are still unknown.In addition,we identified 1,022 non-coding transcripts,several of which change depending on differentiation in gene expression.Our database provides a high-resolution expression profile of E14 cells and is applicable to other mouse ES cell analyses.It includes most transcription regulation-encoding genes and a significant number of unknown and non-coding transcripts.}, pages = {2522--2528}, title = {More then 40,000 transcripts including novel and noncoding transcripts in mouse embryonic stem cells}, volume = {24}, year = {2006} }