@article{oai:repo.qst.go.jp:00044692, author = {Shimazaki, Jun and Akakura, Kouichirou and Suzuki, Hiroyosi and Tomohiko, Ichikawa and Tsuji, Hiroshi and Ishikawa, Hitoshi and Harada, Masaoki and Tsujii, Hirohiko and 島崎 淳 and 赤倉 功一郎 and 鈴木 啓悦 and 市川 智彦 and 辻 比呂志 and 石川 仁 and 原田 昌興 and 辻井 博彦}, issue = {5}, journal = {Japanese Journal of Clinical Oncology}, month = {May}, note = {BACKGROUND: Radiation treatment for localized prostate cancer has become a prominent choice of monotherapy, and carbon ion beam is a powerful means for this purpose. METHODS: In total, 37 patients with localized prostate cancer were treated by monotherapy with carbon ion radiation and the outcome, more than 4 years later, was followed. RESULTS: PSA relapse-free survival was overall 85%, 5 years after radiation, and 96% in low-risk patients. Local control was mostly achieved, and no cancer-specific death was obtained. Except in cases of relapse, 1.0 ng/ml or less of PSA was shown in 78%, 3 years after radiation. Half of biopsy specimens out of 12 cases revealed non-viable or no cancer cells after a rather short time from treatment. CONCLUSION: Monotherapy with carbon ion radiation may be an excellent treatment for localized prostate cancer with low risk.}, pages = {290--294}, title = {Monotherapy with Carbon Ion Radiation for Localized Prostate Cancer}, volume = {36}, year = {2006} }