{"created":"2023-05-15T14:34:34.606090+00:00","id":44680,"links":{},"metadata":{"_buckets":{"deposit":"7c5e0ae7-2a66-4cfb-91aa-2c04abda8a62"},"_deposit":{"created_by":1,"id":"44680","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"44680"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00044680","sets":["1"]},"author_link":["443664","443663"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2004","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"333","bibliographicPageStart":"329","bibliographicVolumeNumber":"1","bibliographic_titles":[{"bibliographic_title":"International Journal of Low Radiation"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Non-tumour-inducing doses exist in dose-response data on experimental animals and humans, although a linear non-threshold model has been adopted for estimating cancer risk of ionising radiation at a low dose region for radiation protection purposes. Here, data on non- tumour dose, Dnt, the maximum dose at which a statistically significant increase of tumours is not observed, were reviewed in the literature. Dnt values range from 0.1 to 3 Gy for a variety of tumours induced by acute whole-body irradiation at low LET. This becomes one order higher by fractionation of radiation dose and further by extending irradiation chronically. Non-tumour doses for irradiation of a part of the body are one order higher than those for whole-body irradiation, indicating a higher tolerance level in the partial-body irradiation. Tumour data with high LET radiation also show non-tumour dose and its decrease at a very low dose rate. The variation of Dnt is explained by the host tolerance, including inducible and non-inducible DNA repair, apoptotic elimination of unrepaired cells, and immunological suppression of tumour development.","subitem_description_type":"Abstract"}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1477-6545","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Tanooka, Hiroshi"}],"nameIdentifiers":[{"nameIdentifier":"443663","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田ノ岡 宏","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"443664","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Threshold dose problems in radiation carcinogenesis: A review of non-tumor doses","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Threshold dose problems in radiation carcinogenesis: A review of non-tumor doses"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2006-10-20"},"publish_date":"2006-10-20","publish_status":"0","recid":"44680","relation_version_is_last":true,"title":["Threshold dose problems in radiation carcinogenesis: A review of non-tumor doses"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-16T00:12:36.365946+00:00"}