@article{oai:repo.qst.go.jp:00044453, author = {Namba, Hiroki and Iwadate, Yasuo and Iyo, Masaomi and Fukushi, Kiyoshi and Irie, Toshiaki and Sakiyama, Shigeru and et.al and 難波 宏樹 and 岩立 康男 and 福士 清 and 入江 俊章 and 崎山 樹}, journal = {Nuclear Medicine and Biology}, month = {}, note = {The effect of aciclovier(ACV) on the metabolism of rat 9I-gliosarcoma cells expressing the herpes simples virus-thymidine kinase gene was studied using 2-deoxy-2-[18F]fluoro-D-glucose(FDG) and L-[methyl-11C]methionine. Though the average weight of the tumors treated with ACV was significantly lower than that of the saline-injected control group, FDG and methionine uptake per weight of tumor tissue was not different between the two groups. This result exhibits a striking contrast to the metabolic pattern observed after radiation therapy, suggesting the different pathways regarding tumor cell death between the therapies.}, pages = {247--250}, title = {Glucose and Methionine Uptake by Rat Brain Tumor Treated with Prodrug-Activated Gene Therapy}, volume = {25}, year = {1998} }