@article{oai:repo.qst.go.jp:00044446, author = {Namba, Hiroki and Nakagawa, Keiichi and Iyo, Masaomi and Fukushi, Kiyoshi and Irie, Toshiaki and 難波 宏樹 and 中川 敬一 and 福士 清 and 入江 俊章}, issue = {3}, journal = {European Journal of Nuclear Medicine}, month = {Mar}, note = {A simple method, without measurement of the plasma input function, to obtain semiquantitative values of glucose utilization in tissues other than tha brain with radioactive deoxyglucose is reported. The brain, in which glucose utilization is essentially insensitive to plasma glucose and insulin concentrations, was used as an internal reference. The effects of graded doses of oral glucose loading (0.5, 1 and 2 mg/g body weight) on insulin-sensitive tissues (heart, muscle and fat tissue) were studied in the rat. By using the brain-reference method, dose-dependent increases in glucose utilization were clearly shown in all the insulin-sensitive tissues examined. the method seems to be of value for measurement of glucose utilization using radioactive deoxyglucose and positron emission tomography in the heart or other insulin-sensitive tissues, especially during glucose loading.}, pages = {228--231}, title = {A simple method for measuring glucose utilization of insulin-sensitive tissues by using the brain as a reference}, volume = {21}, year = {1994} }