@article{oai:repo.qst.go.jp:00044441,
 author = {Irie, Toshiaki and Fukushi, Kiyoshi and Ido, Tatsuo and 入江 俊章 and 福士 清},
 journal = {International Journal of Applied Radiation and Isotopes},
 month = {},
 note = {Introduction of fluorine-18 into the 6-position of purines is described. 18F-6-fluoropurine and 18F-6-fluoro-9-beta-ribofuranosylpurine were prepared with high radiochemical yields by nucleophilic displacement of the trimethylammonio-group of purine with 18F-fluoride under mild conditions. 18F-labeling conditions such as reaction temperature and time. addition of crown ether and dose of a substrate have been studied. Under adequate conditions, yields of about 38% in the case of free base and about 63% in the case of ribofuranosyl derivative have been obtained. The latter compound has also been prepared in a non-carrier-added state. The stability of 18F-purines was examined in Tris buffer at 37 Degree.},
 pages = {445--448},
 title = {Synthesis of 18F-6-fluoropurine and 18F-6-fluoro-9-beta-D-ribofuranosylpurine},
 volume = {33},
 year = {1982}
}