@article{oai:repo.qst.go.jp:00044013, author = {Girard, F and Suhara, Tetsuya and Sassa, Takeshi and Okubo, Yoshiro and Obata, Takayuki and Ikehira, Hiroo and Sudo, Yasuhiko and Koga, M and Yoshioka, H and Yoshida, Katsuya and 須原 哲也 and 佐々 毅 and 大久保 善朗 and 小畠 隆行 and 池平 博夫 and 吉田 勝哉}, issue = {1}, journal = {MAGMA}, month = {Aug}, note = {Lithum salts have been widely used in the treatment of mood disorders, but the mechanism of action is still not clear. In this work, a methodology for two-dimensional Lithium-7 imaging on clinical systems is presented. The data were acquired using a phosphorus volume head coil that was re-tuned for the Lithium-7 frequency. A spectroscopic sequence was used to acquire the free induction decay (FID) after volume excitaion using a hard pulse. The results obtained on the head of patients undergoing lithium treatment(n=7, 0.6mEq/1 average serum level) demonstrate that images of adequate signal to noise ratio (100:1) can be obtained in acceptable imaging times(55 min) using the proposed methodology. The distribution of 7Li appears uniform in the brains of the patients studied.}, pages = {1--7}, title = {7Li 2D CSI of human brain on a clinical scanner.}, volume = {13}, year = {2001} }