{"created":"2023-05-15T14:33:50.695115+00:00","id":43904,"links":{},"metadata":{"_buckets":{"deposit":"58c2be64-8d65-461d-8297-bf08e496ec99"},"_deposit":{"created_by":1,"id":"43904","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"43904"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00043904","sets":["1"]},"author_link":["436442","436445","436441","436444","436439","436438","436440","436443"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1999","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"196","bibliographicPageStart":"193","bibliographicVolumeNumber":"44","bibliographic_titles":[{"bibliographic_title":"Journal of Human Genetics"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Mouse PIAS3 (protein inhibitor of activated STAT3) is a specific inhibitor of STAT3 that downregulates its signaling pathway. Here we report the isolation and chromosome mapping of the human PIAS3 gene. Human PIAS3 cDNA encoded a predicted protein of 619 aa which has 83% overall amino acid identity to the mouse counterpart. Based on polymerase chain reaction assisted analysis of a human/rodent mono-chromosomal hybrid cell panel and a radiation hybrid mapping panel, the human PIAS3 gene was mapped to the chromosome 1q21 region. Mapping of a crucial gene in modulating the STAT3 signaling pathway may provide new clues to the understanding of malignancies or genetic disorders caused by this chromosome region.","subitem_description_type":"Abstract"}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1434-5161","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ueki, Nobuhide"}],"nameIdentifiers":[{"nameIdentifier":"436438","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Seki, Naohiko"}],"nameIdentifiers":[{"nameIdentifier":"436439","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yano, Kazuhiro"}],"nameIdentifiers":[{"nameIdentifier":"436440","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Saito, Toshiyuki"}],"nameIdentifiers":[{"nameIdentifier":"436441","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Masuho, Yasuhiko"}],"nameIdentifiers":[{"nameIdentifier":"436442","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Muramatsu, Masa-aki"}],"nameIdentifiers":[{"nameIdentifier":"436443","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"関 直彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"436444","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"齋藤 俊行","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"436445","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Isolation and chromosomal assignment of a human gene encoding protein inhibitor of activated STAT3 (PIAS3).","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Isolation and chromosomal assignment of a human gene encoding protein inhibitor of activated STAT3 (PIAS3)."}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2005-12-16"},"publish_date":"2005-12-16","publish_status":"0","recid":"43904","relation_version_is_last":true,"title":["Isolation and chromosomal assignment of a human gene encoding protein inhibitor of activated STAT3 (PIAS3)."],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-16T00:21:42.512335+00:00"}